Evidence mapPaperPMID 42255495Full record

ArticleFASEB bioAdvances2026

Lanthanum Chloride in Vascular Calcification: Effects on Nano-Hydroxyapatite and PPARγ/Wnt/β-Catenin.

Ting Zhang, Jialong Qian, Li Zhu, Zhihua Zhou, Xin Wang, Yan Liang, Luyu Wang, Chunsheng Zhang, Ren Bu, Hong Liu and 2 more

Abstract read
In one paragraph

Article in FASEB bioAdvances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ting ZhangDepartment of Pharmacology College of Pharmacy, the Inner Mongolia Medical University, Jinshan Development Hohhot China.
Jialong QianDepartment of Pharmacology College of Pharmacy, the Inner Mongolia Medical University, Jinshan Development Hohhot China.ORCID https://orcid.org/0009-0009-3727-464X
Li ZhuDepartment of Pharmacology College of Pharmacy, the Inner Mongolia Medical University, Jinshan Development Hohhot China.
Zhihua ZhouDepartment of Pharmacology College of Pharmacy, the Inner Mongolia Medical University, Jinshan Development Hohhot China.
Xin WangInner Mongolia University of Science and Technology Baotou Medical College Baotou China.
Yan LiangDepartment of Pharmacology College of Pharmacy, the Inner Mongolia Medical University, Jinshan Development Hohhot China.
Luyu WangDepartment of Pharmacology College of Pharmacy, the Inner Mongolia Medical University, Jinshan Development Hohhot China.
Chunsheng ZhangDepartment of Pharmacology College of Pharmacy, the Inner Mongolia Medical University, Jinshan Development Hohhot China.
Ren BuDepartment of Pharmacology College of Pharmacy, the Inner Mongolia Medical University, Jinshan Development Hohhot China.
Hong LiuDepartment of Pharmacology College of Pharmacy, the Inner Mongolia Medical University, Jinshan Development Hohhot China.
Changjin XuDepartment of Pharmacology College of Pharmacy, the Inner Mongolia Medical University, Jinshan Development Hohhot China.
Gang LiDepartment of Pharmacology College of Pharmacy, the Inner Mongolia Medical University, Jinshan Development Hohhot China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the effects of lanthanum chloride on vascular calcification associated with chronic kidney disease (CKD) and the mechanisms involved in changes in nano-hydroxyapatite. Vascular calcification was induced in CKD rats using a high-phosphorus diet and adenine. Human vascular smooth muscle cells (hVSMCs) were calcified in vitro using sodium β-glycerophosphate (β-GP) and saturated nano-hydroxyapatite. The effects of lanthanum chloride were evaluated using various analytical methods, including serum biochemistry, EVG, Vonkossa staining, Alizarin Red staining, Ca

Indexed as

hydroxyapatitePPARγ/Wnt/β‐catenin signaling pathwayvascular calcification

Identifiers

PMID42255495
PMCPMC13238516

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.