ArticleACS omega2026
1,5-Disubstituted Tetrazoles as Promising Anticancer Resistance Agents: A Chemoinformatic Characterization.
Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The 1,5-disubstituted tetrazole (1,5-DS-T) scaffold is recognized as a privileged structure in medicinal chemistry due to its broad interaction potential with biologically relevant targets. In this study, we conducted an integrated chemoinformatic and molecular modeling analysis of 1,5-DS-T compounds from PubChem, ChEMBL, DrugBank, and an in-house library. Principal component analysis and scaffold diversity analyses showed that the in-house compounds occupy a region of chemical space largely overlapping with bioactive ChEMBL tetrazoles, while also revealing opportunities for further scaffold diversification. Analysis of pIC
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.