Evidence map›Paper›PMID 42258290›Full record

ArticleHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2026

Stress and cardiovascular disease: Testing a vigilance pathway in two contemporary theories.

Riley M O'Neill, George M Slavich, Julian F Thayer, Craig C Weinkauf, Melissa Flores, Chul Ahn, Matthew Allison, Timothy W Smith, Joshua M Smyth, Daniel J Taylor and 2 more

Abstract read
In one paragraph

Article in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Riley M O'NeillDepartment of Psychology, University of Arizona.ORCID 0000-0002-1881-2758
George M SlavichDepartment of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles.ORCID 0000-0001-5710-3818
Julian F ThayerDepartment of Psychological Science, University of California, Irvine.
Craig C WeinkaufDepartment of Surgery, University of Arizona.
Melissa FloresDepartment of Psychology, University of Arizona.ORCID 0000-0002-9436-6665
Chul AhnO'Donnell School of Public Health, University of Texas Southwestern Medical Center.
Matthew AllisonDepartment of Family Medicine, University of California, San Diego.
Timothy W SmithDepartment of Psychology, University of Utah.
Joshua M SmythDepartment of Psychology, Ohio State University.ORCID 0000-0002-0904-5390
Daniel J TaylorDepartment of Psychology, University of Arizona.
Bert N UchinoDepartment of Psychology, University of Utah.
John M RuizDepartment of Psychology, University of Arizona.

Funding

An Integrated Model of Contextual Safety, Social Safety, and Social Vigilance as Psychosocial Contributors to Cardiovascular DiseaseF31HL170513 · NHLBI · UNIVERSITY OF ARIZONA · PI O'NEILL, RILEY MARIA · 2023 to 2025
$97k
California Governor's Office of Planning and Research/California Initiative to Advance Precision MedicineNCI NIH HHSNHLBI NIH HHS F31 HL170513
6 · The paper itself

Abstract

objectiveDespite robust evidence linking psychological stress to cardiovascular disease (CVD), explanations for how risk is transmitted are limited by a lack of ecologically valid models. Recent conceptual advances including generalized unsafety theory of stress and social safety theory articulate persistent physiological activation driven by contextual exposure and compensatory situational vigilance as a pathway. This study provides an integrated first test of generalized unsafety theory of stress and social safety theory models on preclinical CVD.

methodA diverse community sample of 300 adults (

resultsAs hypothesized, greater environmental unsafety (geo-coded crime rates;

conclusionsResults align with a persistent activation conceptualization of stress and modestly support the specific theoretical assertions. These findings suggest future stress-CVD investigations should account for multilevel safety influences and continuous monitoring behavior to more accurately capture daily stress experiences. (PsycInfo Database Record (c) 2026 APA, all rights reserved).

Identifiers

PMID42258290
PMCPMC13245543

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.