Evidence map›Paper›PMID 42258338›Full record

SynthesisAge and ageing2026

Efficacy of traditional Chinese exercises on cognitive function in older adults: a systematic review and meta-analysis of randomised controlled trials.

Bin Li, Lirong Yu, Na Li, Kaisy Xinhong Ye, Jiuyu Guo, Luwen Cao, Jiatong Shan, Yecheng Li, Xiu Wang, Tih-Shih Lee and 5 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Age and ageing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Bin LiDepartment of Geriatrics, Hospital of Chengdu University of Traditional Chinese Medicine, No. 39 Shi-er-qiao Road, Chengdu 610072, Sichuan, China.ORCID 0000-0002-7123-6286
Lirong YuSchool of Nursing, Shandong Second Medical University, Weifang, Shandong, China.
Na LiLaboratory of Molecular Pharmacology, Jilin Provincial Key Laboratory of Biomacromolecules of Chinese Medicine, Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, Jilin, China.
Kaisy Xinhong YeHealthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.ORCID 0000-0002-6924-9213
Jiuyu GuoHealthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Luwen CaoHealthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Jiatong ShanHealthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Yecheng LiCollege of Chemistry, Jilin University, Changchun, China.
Xiu WangDepartment of Neurology, Beijing Chuiyangliu Hospital, Beijing, China.
Tih-Shih LeeNeuroscience and Behavioural Disorders Programme, Duke-NUS Medical School, Neuroscience & Behavioural Disorders Programme, Singapore, Singapore.
Brian K KennedyHealthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
John SucklingDepartment of Psychiatry, University of Cambridge, Herchel Smith Building for Brain and Mind Sciences, Cambridge, UK.
Andrea MaierHealthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Wenbin WuDepartment of Geriatrics, Hospital of Chengdu University of Traditional Chinese Medicine, No. 39 Shi-er-qiao Road, Chengdu 610072, Sichuan, China.
Lei FengCentre for Healthy Longevity, @AgeSingapore, National University Health System, Singapore, Singapore.

Funding

National Medical Research Council of Singapore NMRC/CSA/INV/0009/2022National Medical Research Council of Singapore NMRC/TA/0053/2016Natural Science Foundation of Sichuan Province 25NSFSC0782Sichuan Cadre Health Research Project CGY-2022-504
6 · The paper itself

Abstract

backgroundCognitive impairment is a significant health concern among older adults, highlighting the need for non-pharmacological interventions, such as mind-body exercises. However, a comprehensive synthesis of the effects of various traditional Chinese exercises (TCEs) on cognitive function in older adults is lacking.

methodsA systematic review and meta-analysis of randomised controlled trials (RCTs) was conducted. Six databases were searched from inception to 2 May 2024 for studies examining the effects of TCEs on cognitive outcomes in adults aged 60 years and older. Studies were included if they were RCTs involving TCEs and reported outcome measures for global cognition, or individual cognitive domains.

resultsTwenty-eight RCTs with a total of 2297 participants were included. Meta-analysis revealed that TCEs led to significant improvements in global cognition: Montreal Cognitive Assessment [mean differences (MD) = 1.67; 95% confidence interval (CI): (1.20, 2.14)], Mini-Mental State Examination [MD = 0.76; 95% CI: (0.04, 1.48)]; executive function: Trail Making Test (B-A) [MD = -7.96; 95% CI: (-15.34, -0.59)], Category Fluency for Animals [MD = 2.96, 95% CI (2.08, 3.85)]; working memory: Digit Span-Backwards [MD = 0.48; 95% CI: (0.07, 0.90)]; processing speed: Digit Symbol Coding [MD = 4.16; 95% CI: (1.82, 6.50)]; memory function: Memory Quotient [MD = 13.13; 95% CI: (4.06, 22.20)], Auditory Verbal Learning Test: immediate recall [MD = 1.13; 95% CI: (0.07, 2.20)], short-term delayed recognition [MD = 0.80; 95% CI: (0.28, 1.32)] and long-term delayed recognition [MD = 1.38; 95% CI: (0.68, 2.09)].

conclusionsTCEs are effective in improving cognitive function in older adults, particularly in domains such as global cognition, executive function, working memory, processing speed and memory function. However, given the methodological limitations and heterogeneity of the included studies, these findings require confirmation in further large-scale, high-quality RCTs.

Indexed as

CognitionCognitive DysfunctionMedicine, Chinese TraditionalAgedCognitive EnhancementEast Asian PeopleExecutive FunctionHumansMiddle AgedRandomized Controlled Trials as TopicTreatment Outcomecognitive functionmeta-analysisolder adultsrandomised controlled trialsystematic reviewtraditional Chinese exercises

Identifiers

PMID42258338
PMCPMC13245186

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.