ArticleJournal of applied physiology (Bethesda, Md. : 1985)2026
Large artery stiffness is elevated in women with a prior pregnancy conceived via in vitro fertilization.
Lyndsey E DuBose, Ryan Calabrese, Nanette Santoro, Cassandra Roeca, Elizabeth Clain, Haley Thomas, Julia Seifert, Virginia Nuckols, Brook Thurman, Zachary S Clayton and 1 more
Abstract read
In one paragraphArticle in Journal of applied physiology (Bethesda, Md. : 1985), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
11 authors.
Lyndsey E DuBoseDepartment of Health and Exercise Science, Colorado State University, Fort Collins, Colorado, United States.ORCID 0000-0002-3566-4531 Ryan CalabreseDivision of Geriatric Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.
Nanette SantoroDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.ORCID 0000-0001-9096-7490 Cassandra RoecaDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.ORCID 0000-0001-6668-7317 Elizabeth ClainDivision of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.
Haley ThomasDivision of Geriatric Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.
Julia SeifertDivision of Geriatric Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.
Virginia NuckolsDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark, Delaware, United States.ORCID 0000-0001-5879-5991 Brook ThurmanDivision of Geriatric Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.
Zachary S ClaytonDivision of Geriatric Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.ORCID 0000-0003-3878-3533 Kerrie L MoreauDivision of Geriatric Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States.ORCID 0000-0001-9298-047X Funding
NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1MSuppression of ERalpha in Hematopoietic Stem Cell-Derived Adipocytes Increases Adiposity via Kynurenine and the Aryl Hydrocarbon ReceptorU54AG062319 · NIA · UNIVERSITY OF COLORADO DENVER · PI JUDITH G. REGENSTEINER · 2018 to 2026
$13.5MThe Colorado Building Interdisciplinary Research Careers in Women's Health ProgramK12AR084226 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI JUDITH G. REGENSTEINER, Nanette F. Santoro · 2023 to 2026
$2.5MOvarian Hormone Regulation of Central and Cerebrovascular HemodynamicsF32AG071273 · NIA · UNIVERSITY OF COLORADO DENVER · PI DUBOSE, LYNDSEY · 2021 to 2022
$122kColorado State University Department of Health and Exercise ScienceHHS | National Institutes of Health (NIH) F32AG071273HHS | National Institutes of Health (NIH) K12AR084226HHS | National Institutes of Health (NIH) R00HL159421HHS | National Institutes of Health (NIH) U54AG062319Ludeman Family Center for Women's HealthNCATS NIH HHS UL1 TR002535NIA NIH HHS F32 AG071273
6 · The paper itselfAbstract
In vitro fertilization (IVF) is an effective treatment for infertility; however, IVF may increase future maternal cardiovascular disease (CVD) risk. Vascular dysfunction, characterized by increased large elastic artery stiffness and endothelial dysfunction, predicts future CVD risk. However, whether IVF use influences maternal vascular dysfunction is unknown. We studied premenopausal women with a live birth within the past 1-5 yr conceived either without medical assistance (
Indexed as
Fertilization in VitroVascular StiffnessAdultAnimalsBlood PressureBrachial ArteryCardiovascular DiseasesEndothelium, VascularFemaleHumansMicePregnancyVasodilationcardiovascular diseasefollicle-stimulating hormoneinfertilityvascular functionwomen’s health
Identifiers
PMID42258362
PMCPMC13344158
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