Evidence map›Paper›PMID 42258707›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Host genetic regulation of rumen 6-hydroxymelatonin reduces methane emissions in dairy cattle.

Chenguang Zhang, Ye Liu, Guoyan Wang, Mengqi Huang, Jun Zhang, Zongjun Li, Linhao Zhou, Guangfu Tang, Shengru Wu, Lu Deng and 1 more

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Chenguang Zhang *Department of Animal Nutrition and Environmental Hygiene, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, Shaanxi, China.ORCID 0000-0003-3184-6706
Ye Liu *Department of Animal Nutrition and Environmental Hygiene, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, Shaanxi, China.
Guoyan WangDepartment of Animal Nutrition and Environmental Hygiene, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, Shaanxi, China.
Mengqi HuangDepartment of Animal Nutrition and Environmental Hygiene, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, Shaanxi, China.ORCID 0009-0001-3804-4717
Jun ZhangDepartment of Animal Nutrition and Environmental Hygiene, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, Shaanxi, China.
Zongjun LiDepartment of Animal Nutrition and Environmental Hygiene, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, Shaanxi, China.ORCID 0000-0002-8986-3472
Linhao ZhouDepartment of Animal Nutrition and Environmental Hygiene, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, Shaanxi, China.ORCID 0009-0005-9158-2628
Guangfu TangDepartment of Animal Nutrition and Environmental Hygiene, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, Shaanxi, China.
Shengru WuDepartment of Animal Nutrition and Environmental Hygiene, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, Shaanxi, China.
Lu DengDepartment of Animal Nutrition and Environmental Hygiene, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, Shaanxi, China.
Junhu YaoDepartment of Animal Nutrition and Environmental Hygiene, College of Animal Science and Technology, Northwest A&F University, Yangling 712100, Shaanxi, China.

Funding

National Center of Technology Innovation for Dairy 2024-KFKT-011Postdoctoral Foundation of Shaanxi Province 2025BSHSDZZ154
6 · The paper itself

Abstract

The mechanisms linking host genetics to ruminal methane emissions remain unclear. Here, we integrated multiomics data from 304 lactating cows and demonstrated that methane emission per dry matter intake (M/D) exhibitd higher heritability (

Indexed as

MelatoninMethaneRumenAnimalsCattleFemaleFermentationGenome-Wide Association StudyPrevotellaMelatoninMethane6-hydroxymelatonindairy cattlehost geneticmethane mitigationrumen microbiota

Identifiers

PMID42258707
PMCPMC13291679

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.