Evidence map›Paper›PMID 42259646›Full record

ArticleDiabetes, obesity & metabolism2026

Glycemic Normalization Immediately Following Vertical Sleeve Gastrectomy in Adolescents With Type 2 Diabetes From the ST

Natalie Segev, Kristen J Nadeau, Megan Kelsey, Lisa R Schaaf, Amy Baumgartner, Allen Riegler, Kelly Wiitala, Todd M Jenkins, Stavra A Xanthakos, Michael A Helmrath and 2 more

Abstract read
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In one paragraph

Article in Diabetes, obesity & metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Natalie SegevDivision of Diabetes and Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.ORCID 0000-0003-1212-9082
Kristen J NadeauSection of Pediatric Endocrinology, University of Colorado Anschutz, Aurora, Colorado, USA.ORCID 0000-0002-0477-3356
Megan KelseySection of Pediatric Endocrinology, University of Colorado Anschutz, Aurora, Colorado, USA.
Lisa R SchaafDivision of Diabetes and Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Amy BaumgartnerSection of Pediatric Endocrinology, University of Colorado Anschutz, Aurora, Colorado, USA.
Allen RieglerDivision of Diabetes and Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Kelly WiitalaSection of Pediatric Endocrinology, University of Colorado Anschutz, Aurora, Colorado, USA.
Todd M JenkinsDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Stavra A XanthakosDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Michael A HelmrathDivision of Pediatric General and Thoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Thomas H IngeDepartment of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Amy Sanghavi ShahDivision of Diabetes and Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

Funding

Surgical or Medical Treatment for Pediatric Type 2 Diabetes (ST2OMP)R01DK119450 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI HELMRATH, MICHAEL A., INGE, THOMAS HARRIS · 2019 to 2023
$3.3M
Abbott Diabetes CareNIDDK NIH HHS R01 DK119450NIDDK NIH HHS R01DK119450
6 · The paper itself

Abstract

aimYouth-onset type 2 diabetes and obesity are rising public health burdens. While newer type 2 diabetes medications lower HbA1c, their impact on paediatric weight loss is inconsistent. In contrast, bariatric surgery improves glycemia and weight in youth and adults, though glycemia post-vertical sleeve gastrectomy (VSG), now the predominant bariatric surgery in youth, remains unstudied in youth-onset type 2 diabetes. We aimed to assess immediate post-VSG glycemic patterns using continuous glucose monitoring (CGM) in adolescents with type 2 diabetes. MATERIALS AND

methodsIn the Surgical or Medical Treatment for Paediatric Type 2 Diabetes (ST

resultsMean glucose was 84.3 ± 23.4 in the post-VSG group versus 149.8 ± 78.8 mg/dL in the AMT group (p < 0.001). Mean CGM GMI was normal (5.3%, 34 mmol/mol) post-VSG versus in the diabetes range (6.9%, 52 nmol/mol) with AMT (p < 0.001). VSG participants spent more time < 70 mg/dL, 55 mg/dL, and 45 mg/dL (all p < 0.01). After BMI adjustment, preoperative HbA1c predicted postoperative glucose metrics.

conclusionAdolescents with type 2 diabetes experience early glycemic normalization post-VSG, even before major weight loss.

Indexed as

Bariatric SurgeryBlood GlucoseDiabetes Mellitus, Type 2GastrectomyPediatric ObesityAdolescentContinuous Glucose MonitoringFemaleGlycated HemoglobinGlycemic ControlHumansHypoglycemic AgentsMaleTreatment OutcomeWeight LossBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanHypoglycemic Agentsadolescentcontinuous glucose monitoringvertical sleeve gastrectomyyouth‐onset type 2 diabetes

Identifiers

PMID42259646
PMCPMC13341355

What Socratic holds

Textmetadata
LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.