Evidence map›Paper›PMID 42259905›Full record

ArticleNPJ precision oncology2026

Variable efficacy of the non-covalent KRAS

Sujith Sarvesh, Holly Stephens, Pia Muri, Henry Nnaemeka Ogbonna, Jianqing Zhang, Karen Aikhionbare, Dhana Sekar Reddy Bandi, Cherlene Hardy, Ganji Purnachandra Nagaraju, Bassel F El-Rayes and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ precision oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sujith SarveshDepartment of Hematology and Oncology, University of Alabama at Birmingham, Birmingham, AL, USA.
Holly StephensDepartment of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, USA.
Pia MuriDepartment of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, USA.
Henry Nnaemeka OgbonnaDepartment of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL, USA.
Jianqing ZhangDepartment of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL, USA.
Karen AikhionbareDepartment of Hematology and Oncology, University of Alabama at Birmingham, Birmingham, AL, USA.
Dhana Sekar Reddy BandiDepartment of Hematology and Oncology, University of Alabama at Birmingham, Birmingham, AL, USA.
Cherlene HardyAnimal Resources Program, University of Alabama at Birmingham, Birmingham, AL, USA.
Ganji Purnachandra NagarajuDepartment of Hematology and Oncology, University of Alabama at Birmingham, Birmingham, AL, USA.
Bassel F El-RayesDepartment of Hematology and Oncology, University of Alabama at Birmingham, Birmingham, AL, USA.
Lyse A NorianDepartment of Microbiology, Immunology, and Molecular Genetics, University of Kentucky, Lexington, KY, USA. lano234@uky.edu.
Jeremy B FooteAnimal Resources Program, University of Alabama at Birmingham, Birmingham, AL, USA. jbf130@uab.edu.

Funding

Overcoming obesity-associated immunotherapy resistance in renal cancerR01CA269568 · NCI · UNIVERSITY OF KENTUCKY · PI Lyse A Norian · 2023 to 2026
$2.1M
Multi-parameter, analytic flow cytometerS10OD032296 · OD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI RANDALL, TROY D · 2022 to 2022
$464k
NCATS NIH HHS 1R01 CA269568-01NCI NIH HHS R01 CA269568NIH HHS S10 OD032296University of Alabama at Birmingham Microbiology-Nutrition Obesity Research Center Pilot Grant
6 · The paper itself

Abstract

Previous studies indicate that Diet-induced-obesity (DIO) promotes pancreatic tumor progression, immunosuppression, and resistance to chemotherapy. Here, we evaluated the impact of DIO on efficacy of KRAS

Identifiers

PMID42259905
PMCPMC13582987

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.