ArticleThe New phytologist2026
Apple ZAT11, a C2H2-type zinc finger protein, enhances resistance to Penicillium expansum by affecting jasmonic acid biosynthesis in apple.
Article in The New phytologist, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Blue mold, caused by Penicillium expansum, is a prevalent postharvest disease of apple and significantly limits apple quality. Apple have key genes underlying their biological stress responses and corresponding functions that remain largely unexplored. Here, we identified MdZAT11, a Cys2/His2 (C2H2)-type zinc finger protein, as a crucial positive regulator of apple resistance to P. expansum infection. Utilizing transcription factor-centered yeast one-hybrid (TF-centered Y1H) and RNA sequencing analyses, we discovered 1059 potential target genes of MdZAT11, with Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment indicating significant enrichment in stress-responsive pathways, particularly jasmonic acid (JA) biosynthesis. Further investigation revealed that MdZAT11 enhances the expression of JA biosynthesis genes (MdAOS, MdAOC, MdLOX6, and MdLOX3.1) by directly binding to their promoters, as demonstrated by electrophoretic mobility shift assays (EMSA), dual-luciferase reporter (DLR) assays, and RT-qPCR analysis, thereby augmenting JA biosynthesis. Taken together, our findings advance understanding of the transcriptional regulation of defense against P. expansum in apple and identify MdZAT11 as a candidate gene worth further investigation for disease resistance in this species.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.