Evidence map›Paper›PMID 42260339›Full record

ArticleBMC plant biology2026

Analysis of the effect of variable frequency fan on tobacco metabolites during curing via untargeted metabolomics.

Di Shi, Xiaoqiang Zhang, Guanhui Li, Hongfeng Liu, Zhengfa Shi, Jiawei Luo, Xin Jin, Shengjiang Wu, Ning Huang, ZeYu Zhao and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Di Shi *College of Agriculture, Yangtze University, Jingzhou, Hubei, 434025, China.
Xiaoqiang Zhang *Guizhou Tobacco Company Guiyang City Company Xiuwen Branch, Xiuwen, Guizhou, 550200, China.
Guanhui Li *College of Agriculture, Yangtze University, Jingzhou, Hubei, 434025, China.
Hongfeng LiuGuizhou Tobacco Company Guiyang City Company Xiuwen Branch, Xiuwen, Guizhou, 550200, China.
Zhengfa ShiGuizhou Tobacco Company Guiyang City Company Xiuwen Branch, Xiuwen, Guizhou, 550200, China.
Jiawei LuoGuizhou Tobacco Company Guiyang City Company Xiuwen Branch, Xiuwen, Guizhou, 550200, China.
Xin JinGuizhou Tobacco Company Guiyang City Company Xiuwen Branch, Xiuwen, Guizhou, 550200, China.
Shengjiang WuGuizhou Academy of Tobacco Science, Guiyang, Guizhou, 550081, China.
Ning HuangGuizhou Tobacco Company Guiyang City Company Xiuwen Branch, Xiuwen, Guizhou, 550200, China.
ZeYu ZhaoCollege of Agriculture, Yangtze University, Jingzhou, Hubei, 434025, China.
Lingli XieCollege of Agriculture, Yangtze University, Jingzhou, Hubei, 434025, China. linglixie@yangtzeu.edu.cn.
Kesu WeiGuizhou Academy of Tobacco Science, Guiyang, Guizhou, 550081, China. weiks8816@163.com.

Funding

China National Tobacco Corporation Guizhou Provincial Company Science and Technology Project 2024XM21China National Tobacco Corporation Science and Technology Project 110202202016Guizhou Provincial Tobacco Company Guiyang City Company Science and Technology Project 2023-12the Guizhou Provincial Major Scientific and Technological Program QKHZDZXZ[2024]004]
6 · The paper itself

Abstract

The Variable-frequency (VF) fan regulation is a promising technique for flue-curing of tobacco (Nicotiana tabacum L.), and exploring its mechanism is of great significance for improving the curing quality. The middle leaves of "Yunyan 87" were used as experimental materials for exploring the changes of metabolic components by untargeted metabolomics and monitoring dynamic changes of key physiological indicators during flue-curing, VF curing (dynamic frequency: 35-40-45-40 Hz) and constant-frequency curing (50 Hz, CK). VF treatment resulted in a more uniform yellowing process, reduced leaf browning, and improved color retention compared with the control. Leaves under VF treatment showed enhanced superoxide dismutase (SOD), peroxidase (POD), and polyphenol oxidase (PPO) activities, accompanied by lower malondialdehyde (MDA) accumulation. At 48 h, Pathway enrichment analysis revealed the glyoxylate and dicarboxylate metabolism pathway was most affected, with significantly enriched metabolites including isocitrate, citric acid, and glyoxylate. At 120 and 168 h, the most significant metabolic pathways affected by variable frequency fan were flavonoid and flavanol biosynthesis, accompanied significantly enrichment of kaempferol, quercetin, and quercetin. Notably, total aroma substances were reduced under VF (Neophytadiene - 42%, benzaldehyde - 28%). This study provided a metabolomics-based framework for improving intensive curing processes.

Indexed as

MetabolomeMetabolomicsNicotianaCatechol OxidaseMalondialdehydePlant LeavesSuperoxide DismutaseCatechol OxidaseMalondialdehydeSuperoxide DismutaseAroma componentsFan frequencyMetabolic pathwayPhysiological changesUntargeted metabolome

Identifiers

PMID42260339
PMCPMC13471353

What Socratic holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.