Evidence map›Paper›PMID 42260342›Full record

ArticleBMC genomic data2026

Complete genome sequence of Streptococcus lingualis isolated from subgingival biofilm.

Seok Bin Yang, Doyun Ku, Kyu Hwan Kwack, Eun-Young Jang, Soo-Kyung Jun, Ji-Hoi Moon, Jae-Hyung Lee

Abstract read
In one paragraph

Article in BMC genomic data, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Seok Bin Yang *Department of Oral Microbiology, College of Dentistry, Kyung Hee University, Seoul, 02447, Republic of Korea.
Doyun Ku *Department of Oral Microbiology, College of Dentistry, Kyung Hee University, Seoul, 02447, Republic of Korea.
Kyu Hwan KwackDepartment of Oral Microbiology, College of Dentistry, Kyung Hee University, Seoul, 02447, Republic of Korea.
Eun-Young JangDepartment of Oral Microbiology, College of Dentistry, Kyung Hee University, Seoul, 02447, Republic of Korea.
Soo-Kyung JunDepartment of Dental Hygiene, Ansan University, Ansan, 15328, Republic of Korea.
Ji-Hoi MoonDepartment of Oral Microbiology, College of Dentistry, Kyung Hee University, Seoul, 02447, Republic of Korea. prudence75@khu.ac.kr.
Jae-Hyung LeeDepartment of Oral Microbiology, College of Dentistry, Kyung Hee University, Seoul, 02447, Republic of Korea. jaehlee@khu.ac.kr.

Funding

Korea Basic Science Institute RS-2024-00404660National Research Foundation of Korea RS-2021-NR061563National Research Foundation of Korea RS-2025-16066503National Research Foundation of Korea RS-2025-20512973
6 · The paper itself

Abstract

objectiveStreptococcus lingualis is a recently described oral streptococcal species; however, genomic information for this species remains limited, with only a single complete genome currently available for the type strain S5ᵀ. The objective of this study was to generate a high-quality complete genome sequence of a subgingival biofilm-derived S. lingualis isolate and expand the genomic resources available for this species. DATA DESCRIPTION: The S. lingualis strain KHUD_012 was isolated from subgingival biofilm of a healthy adult and sequenced using the PacBio Sequel IIe platform. A single SMRT cell produced 144,821 HiFi reads, which were assembled de novo using the IPA HiFi genome assembler v2.0. The complete genome consists of a single circular chromosome of 2,115,610 bp with a G + C content of 42.0%, encoding 1,956 protein-coding genes, four rRNA operons, and 62 tRNAs. BUSCO analysis indicated 99.5% completeness. Pairwise whole-genome comparisons with closely related type strains showed that KHUD_012 was most closely related to S. lingualis S5ᵀ, with an OrthoANI value of 96.44%, and Parsnp-based core-genome SNP analysis supported this phylogenetic placement. Comparative genomic analysis with S5ᵀ identified 1,717 shared core gene clusters and 198 unique gene clusters in KHUD_012, many of which were functionally uncharacterized.

Indexed as

BiofilmsGenome, BacterialGingivaStreptococcusBase CompositionHumansPhylogenyWhole Genome SequencingGenomeStreptococcus lingualisSubgingival biofilm

Identifiers

PMID42260342
PMCPMC13471454

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.