ArticleMedicine2026
Effects of an informatized system based on the WHO "Safe Childbirth Checklist" combined with oxytocin on post-cesarean section hemorrhage.
Article in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
This study evaluates the effectiveness of an informatized system based on the World Health Organization "Safe Childbirth Checklist" combined with standardized oxytocin administration in preventing postpartum hemorrhage (PPH) after cesarean section. A retrospective study included 100 women undergoing cesarean section between January 2023 and August 2025. Patients were divided into a control group (routine care) and an intervention group (informatized checklist plus optimized oxytocin strategy), with 50 cases each. Outcomes included blood loss at 2 hours and 24 hours, PPH incidence, hemoglobin reduction, additional uterotonic use, hospital stay, pelvic floor function, process quality indicators, and quality of life. Multivariate logistic regression was used to identify factors associated with PPH. Compared with the control group, the intervention group had significantly lower blood loss at 2 hours (312.48 ± 70.21 vs 420.56 ± 85.34 mL) and 24 hours (415.76 ± 95.63 vs 540.12 ± 110.45 mL), and a reduced PPH incidence (12.0% vs 30.0%, all P < .05). Hemoglobin reduction, additional uterotonic use, and hospital stay were also significantly decreased (all P < .05). Pelvic floor function improved, with higher vaginal dynamic pressure and muscle tone scores (P < .05). Process indicators, including checklist completion, timely oxytocin administration, and blood loss measurement accuracy, were significantly improved, along with shorter emergency response time and higher staff satisfaction (all P < .05). Quality-of-life scores were also higher in all dimensions (P < .05). The intervention was identified as an independent protective factor for PPH (odd ratio = 0.157, P < .05). The informatized World Health Organization checklist combined with standardized oxytocin use was associated with reduced post-cesarean hemorrhage, improved process quality, and better maternal outcomes. Given the retrospective single-center design and limited sample size, these findings should be interpreted as associative and require confirmation in prospective multicenter studies.
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