Evidence map›Paper›PMID 42261359›Full record

ArticleInternational journal of nanomedicine2026

Bone Marrow-Derived Macrophages Loaded with Boron Carbide Nanoparticles Targeting the Glioblastoma Microenvironment for Boron Neutron Capture Therapy.

Anna Rudawska, Agnieszka Szczygieł, Katarzyna Węgierek-Ciura, Jagoda Mierzejewska, Dawid Kozień, Paulina Żeliszewska, Monika Chaszczewska-Markowska, Piotr Rusiniak, Katarzyna Wątor, Zbigniew Pędzich and 2 more

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Anna RudawskaHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.ORCID 0000-0001-8802-5859
Agnieszka SzczygiełHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.ORCID 0000-0003-1516-5636
Katarzyna Węgierek-CiuraHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.
Jagoda MierzejewskaHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.
Dawid KozieńDepartment of Materials Science and Ceramics, AGH University of Krakow, Krakow, Poland.
Paulina ŻeliszewskaJerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Krakow, Poland.
Monika Chaszczewska-MarkowskaHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.
Piotr RusiniakDepartment of Geology, Geophysics and Environmental Protection, AGH University of Krakow, Krakow, Poland.ORCID 0000-0001-6699-2282
Katarzyna WątorDepartment of Geology, Geophysics and Environmental Protection, AGH University of Krakow, Krakow, Poland.ORCID 0000-0002-1921-5146
Zbigniew PędzichDepartment of Materials Science and Ceramics, AGH University of Krakow, Krakow, Poland.
Elżbieta Pajtasz-PiaseckaHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.
Bożena Szermer-OlearnikHirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.ORCID 0000-0002-1451-4227

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Boron neutron capture therapy (BNCT) is a targeted radiotherapy that represents a promising treatment for glioblastoma multiforme. BNCT efficacy depends on selective boron carriers capable of crossing the blood-brain barrier (BBB). Therefore, we propose an original strategy for boron delivery in BNCT, based on the cellular carriers. This study assessed the ability of bone marrow-derived macrophages (BMDMs) to accumulate boron carbide (B Methods: The uptake and accumulation of B Results: All BMDM populations demonstrated the ability to accumulate B Conclusion: BMDMs are promising carriers of B

Indexed as

Boron CompoundsBoron Neutron Capture TherapyBrain NeoplasmsGlioblastomaMacrophagesNanoparticlesAnimalsBlood-Brain BarrierCell Line, TumorCell MovementCell SurvivalHumansMiceTumor MicroenvironmentBoron Compoundsblood-brain barrierboron carbide nanoparticlesboron neutron capture therapycellular carriersglioblastoma multiformemacrophages

Identifiers

PMID42261359
PMCPMC13242812

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.