Evidence map›Paper›PMID 42261503›Full record

ArticleCureus2026

Complex Challenges in ANCA-Associated Vasculitis: A Case of COVID-19, Cytomegalovirus Pneumonitis, and Hemorrhagic Cholecystitis Following Rituximab Therapy.

Fatema Ezzy, Dina Ismail, Tiago Reyes Castro, Chen Chao, Nana Jinjolava

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fatema EzzyInternal Medicine, Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, USA.
Dina IsmailInternal Medicine, Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, USA.
Tiago Reyes CastroInternal Medicine, New York Medical College, Metropolitan Hospital Center, New York, USA.
Chen ChaoRheumatology, Montefiore Medical Center, Albert Einstein University, Bronx, USA.
Nana JinjolavaRheumatology, Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a rare autoimmune disease with significant infectious and hemorrhagic risks during immunosuppressive therapy. We describe an 81-year-old woman with perinuclear ANCA (p-ANCA)-associated vasculitis complicated by acute respiratory distress syndrome from concurrent COVID-19 and CMV pneumonitis following rituximab induction. Her course was further complicated by hemorrhagic cholecystitis, a rare bleeding manifestation, requiring percutaneous intervention. Careful adjustment of immunosuppression was necessary due to severe infections. This case highlights the complexity of managing AAV amid severe infections and rare hemorrhagic complications, emphasizing the need for vigilant monitoring and individualized therapy.

Indexed as

antineutrophil cytoplasmic antibody (anca) associated vasculitis (aav)congenital cytomegalovirus infectioncovid-19hemorrhagic cholecystitisimmune reconstitution inflammatory syndromerituximab therapy

Identifiers

PMID42261503
PMCPMC13242648

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.