Evidence map›Paper›PMID 42261847›Full record

SynthesisHIV medicine2026

Retention in care among women with HIV: A systematic review of treatment continuity during pregnancy and postpartum.

Stine Hansen, Klara Tetzschner Madsen, Nina Weis, Ellen Moseholm

Abstract readSystematic Review
In one paragraph

Synthesis in HIV medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stine HansenFaculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0009-0004-1276-3547
Klara Tetzschner MadsenFaculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.ORCID https://orcid.org/0009-0009-7727-8725
Nina WeisDepartment of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.ORCID https://orcid.org/0000-0002-3133-2724
Ellen MoseholmDepartment of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark.ORCID https://orcid.org/0000-0002-7195-8641

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPregnant women with HIV are at risk of reduced engagement in HIV care during pregnancy and postpartum. Retention in care, defined as continuous engagement in HIV-related treatment and follow-up, is essential to achieve virological suppression and prevent vertical transmission. Contemporary evidence on retention in care during pregnancy and postpartum among women with HIV in high-income countries remains limited. Thus, the aim of this systematic review was to examine retention in care during pregnancy and postpartum in this population and context.

methodsA systematic literature review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Embase and CINAHL were searched for observational studies including pregnant and/or postpartum women with HIV in high-income countries reporting retention in care outcomes. Screening, data extraction and quality assessment were performed independently by two reviewers.

resultsOf 5089 records identified, 11 cohort studies were included. Retention in care was higher during pregnancy than postpartum, with declines observed up to 24 months postpartum. Several studies reported improvements in retention in care between 1996 and 2019. Use of antiretroviral therapy (ART) with viral suppression during pregnancy was associated with more favourable postpartum retention in care and virological outcomes. Heterogeneity in outcome definitions and follow-up periods precluded meta-analysis.

conclusionIn high-income countries, most studies show high retention in care during pregnancy and declines after delivery. Retention in care has improved over time, and sufficient ART during pregnancy is associated with enhanced postpartum outcomes. Future research should prioritize standardized outcome definitions to strengthen evidence.

Indexed as

Anti-HIV AgentsContinuity of Patient CareHIV InfectionsInfectious Disease Transmission, VerticalPregnancy Complications, InfectiousRetention in CareFemaleHumansPostpartum PeriodPregnancyAnti-HIV AgentsHIVpostpartumpregnancyretention in carewomen

Identifiers

PMID42261847
PMCPMC13631686

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.