ArticleDrug and alcohol review2026
Intranasal Mucosal Atomiser Devices: A Novel Harm Reduction Intervention.
Article in Drug and alcohol review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionFactors associated with diminished peripheral vein access, including age, prolonged history of injecting drug use and coadministration with other substances, are all increasing among people who inject drugs in Australia. This exposes individuals to increased risk of injecting related complications, including skin and soft tissue infection, neurovascular injury and deep vein thrombosis. CASE PRESENTATION: Case 1 is a 48-year-old man with a 30-year history of injecting drug use who presents with recurrent skin and soft tissue infections requiring hospitalisation, surgery and extensive wound care. Case 2 is a 40-year-old woman who has been injecting heroin since her teens, predominantly into the femoral vein. She has developed significant chronic venous insufficiency and severe venous ulcers. Both consumers were motivated to reduce their injecting-related harms and were offered the use of an intranasal atomiser for heroin administration and reported both a positive use experience and an intention to continue to utilise the device. DISCUSSION AND
conclusionsIntranasal administration of heroin via atomising device may be an effective harm reduction intervention. The efficacy of these devices is supported by evaluation within heroin-assisted treatment programs, where they are associated with high rates of treatment retention, a favourable user experience and 50% fewer injection episodes. Harm reduction benefits of these devices require further evaluation but are likely to include reduced rates of infection and overdose. Given the potential benefits, as supported by the two cases reported here, intranasal atomisers should be further evaluated for inclusion within community harm reduction programs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.