SynthesisBMC pregnancy and childbirth2026
Associations of physical activity during pregnancy with antenatal and postpartum depression: a systematic review and dose-response meta-analysis.
Synthesis in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
objectiveTo explore the dose-response associations of physical activity (PA) during pregnancy with antenatal depression (AD) and postpartum depression (PPD).
methodThirteen electronic databases were searched from inception to April 8, 2026 and additionally screened references manually. Interventional and longitudinal observational studies in pregnant populations were eligible if they reported dose-response associations for PA during pregnancy in relation to AD or PPD; cross-sectional studies were excluded. Linear and nonlinear dose-response meta-analyses were conducted.
resultsTwenty-three studies from 10 countries involving 122,847 participants were included, comprising 5 randomized clinical trials and 18 cohort studies. In the linear dose-response meta-analysis, each 300 MET-min/wk increase in PA was associated with a 6% lower risk of AD (RR, 0.94; 95% CI, 0.90-0.97), with substantial heterogeneity (I2 = 70.6%, P < 0.001). AD also showed a significant nonlinear dose-response relationship, with the lowest risk observed at approximately 1000-2000 MET-min/wk and no evident protective association above approximately 4000 MET-min/wk. PA during pregnancy was associated with a lower risk of depression in late pregnancy, whereas the overall associations with mid-pregnancy depression and PPD were not statistically significant.
conclusionsPA during pregnancy was associated with a lower risk of AD and showed a significant nonlinear dose-response relationship, with the lowest risk observed at approximately 1000 to 2000 MET-min/wk, whereas no significant overall association was observed with PPD.
Indexed as
Identifiers
42265669What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.