Evidence mapPaperPMID 42265997Full record

GuidelineJournal of the American College of Cardiology2026

2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

Chiadi E Ndumele, Fatima Rodriguez, Dave L Dixon, Sadiya S Khan, Debabrata Mukherjee, Mandeep Bajaj, Sripal Bangalore, Biykem Bozkurt, Khadijah Breathett, Shoa L Clarke and 26 more

Abstract readPractice Guideline
In one paragraph

Guideline in Journal of the American College of Cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors.

Chiadi E Ndumele
Fatima Rodriguez
Dave L Dixon
Sadiya S Khan
Debabrata Mukherjee
Mandeep Bajaj
Sripal Bangalore
Biykem Bozkurt
Khadijah Breathett
Shoa L Clarke
Ian H de Boer
David H Ellison
Lorraine S Evangelista
Sean P Heffron
Dhruv S Kazi
Ambar Kulshreshtha
Ildiko Lingvay
Cecilia C Low Wang
Claudia A Mercado
John Magaña Morton
Ian J Neeland
Neha Pagidipati
Tiffany M Powell-Wiley
Janani Rangaswami
Goutham Rao
Nosheen Reza
Anum Saeed
Wendy St Peter
J Bradley Starks
Madeline Sterling
Amy W Talbot
Andrew H Tran
Katherine R Tuttle
Lisa B VanWagner
Amanda R Vest
Salim S Virani

Funding

NHLBI NIH HHS R01 HL093466
6 · The paper itself

Abstract

aimThe "2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome" retires, replaces, and expands upon the "2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults." The primary intended audience for this guideline is clinicians who care for patients across the spectrum of cardiovascular-kidney-metabolic syndrome, an interrelated condition characterized by the interconnections among metabolic risk factors (including obesity and type 2 diabetes), chronic kidney disease, and cardiovascular disease.

methodsA comprehensive literature search was conducted from October 29, 2024, to April 14, 2025, to identify clinical studies, systematic reviews and meta-analyses, and other evidence conducted on human subjects that were published since 2015 in English from MEDLINE (through PubMed), EMBASE, the Cochrane Library, the Agency for Healthcare Research and Quality, and other selected databases relevant to this guideline. STRUCTURE: The focus of this clinical practice guideline is to create a living, working document that provides current knowledge in the field of cardiovascular-kidney-metabolic syndrome aimed at all practicing cardiologists, endocrinologists, nephrologists, and primary care and specialty clinicians who manage these patients.

Indexed as

CardiologyCardio-Renal SyndromeCardiovascular DiseasesMetabolic SyndromeAmerican Heart AssociationHumansReview Literature as TopicUnited StatesACC/AHA clinical practice guidelineatherosclerosisatrial fibrillationblood pressure/hypertensioncardiovascular diseasecardiovascular-kidney-metaboliccoronary diseasediabetesdiagnosisheart failurekidney disease(s), chronicmanagement, cardiovascular-kidney-metabolicMASLDmetabolic syndromeoverweight/obesityperipheral artery diseaserenal insufficiencyrisk factorsscreeningssecondary preventionvenous thromboembolismweight loss

Identifiers

PMID42265997
PMCPMC13399222

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.