ArticleAnnals of coloproctology2026
Guideline-concordant antibiotic prophylaxis on surgical site infection rates following colorectal surgery: real-world data from Thailand.
Article in Annals of coloproctology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAntibiotic prophylaxis (AP) is a key component in preventing surgical site infections (SSIs). The existing gap between clinical guidelines and real-world practice may influence SSI rates. This study aimed to compare SSI rates between patients receiving guideline-concordant AP based on the 2020 Thailand guideline (group A) and those receiving broader-spectrum and/or prolonged prophylaxis (group B).
methodsWe reviewed a database of adult patients who underwent elective colorectal resection between January 2022 and April 2024 at the largest university hospital in Thailand. SSIs were diagnosed using the US Centers for Disease Control and Prevention's criteria. SSI rates between the 2 groups were compared, and factors associated with SSIs were determined.
resultsThis study included 1,584 patients, with an average age of 66 years, and 822 (51.9%) were male. The most common operation was anterior resection (n=470, 29.7%). A total of 1,030 patients (65.0%) underwent open surgery, and 228 patients (14.4%) had stoma formation. There were 405 patients (25.6%) in group A. Overall, SSIs occurred in 104 patients (6.6%): 69 incisional SSIs (4.4%) and 35 organ/space SSIs (2.2%). There was no significant difference in SSI rates between groups (group A vs. group B: 4.7% [95% confidence interval (CI), 2.9%-7.2%] vs. 7.2% [95% CI, 5.8%-8.8%]; P=0.078). Multivariate analysis identified 3 independent predictors of SSIs: hypoalbuminemia (odds ratio [OR], 2.53; 95% CI, 1.54-4.16; P<0.001), obesity (OR, 1.89; 95% CI, 1.08-3.32; P=0.026), and intraoperative blood loss greater than 400 mL (OR, 1.83; 95% CI, 1.06-3.16; P=0.031).
conclusionThere was no significant difference in SSI rates following colorectal surgery between patients receiving guideline-concordant AP and those receiving broader-spectrum and/or prolonged prophylaxis.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.