Evidence map›Paper›PMID 42266154›Full record

ArticleOrthopaedic surgery2026

Endoscopic-Assisted Posterior Atlantoaxial Fusion: Technical Innovation and Clinical Experience.

Jichong Zhu, Chengqian Huang, Jiang Xue, Jiarui Chen, Yufan Xu, Dequan Liu, Xinli Zhan, Chong Liu

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Article in Orthopaedic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Jichong ZhuThe First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Chengqian HuangThe Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
Jiang XueThe First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Jiarui ChenThe First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Yufan XuThe First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Dequan LiuThe First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Xinli ZhanThe First Affiliated Hospital of Guangxi Medical University, Nanning, China.ORCID https://orcid.org/0000-0002-6936-481X
Chong LiuThe First Affiliated Hospital of Guangxi Medical University, Nanning, China.ORCID https://orcid.org/0000-0003-2479-3001

Funding

Joint Project on Regional High-Incidence Diseases Research of the Guangxi Natural Science Foundation 2024GXNSFAA010073National Natural Science Foundation of China NSFC82360422
6 · The paper itself

Abstract

backgroundAtlantoaxial instability or dislocation requires reliable posterior stabilization and fusion to prevent neurological deterioration. Although conventional Goel-Harms posterior fixation provides effective biomechanical stability, it usually requires extensive posterior cervical muscle dissection and may be associated with substantial blood loss, postoperative axial pain, and soft-tissue morbidity. Despite the advantages of minimally invasive endoscopic techniques in spinal surgery, clinical evidence regarding their application in the management of AAI/D remains limited. In this study, we report a clinical series of endoscopic-assisted atlantoaxial lateral mass fusion, provide a detailed description of the key surgical steps, and evaluate its technical feasibility, safety, and early clinical outcomes.

methodsSixteen patients diagnosed with AAI/D underwent endoscopic-assisted posterior atlantoaxial fusion. The procedure utilized a uniportal endoscopic system through a 2.5-3.0 cm incision, enabling direct visualization of the C1-C2 lateral mass joint, precise screw placement, and intra-articular bone grafting under continuous irrigation. Radiographic parameters, neurological function (JOA), pain (VAS), and neck disability (NDI) scores were assessed pre- and postoperatively.

resultsAll surgeries were successfully completed without intraoperative neurovascular injury or hardware malposition. The mean operative time was 103.06 ± 9.55 min, and the mean blood loss was 40.06 ± 9.28 mL. The atlantodental interval (ADI) decreased from 5.14 ± 1.51 mm preoperatively to 3.37 ± 0.52 mm postoperatively (p < 0.001), and C1-C2 joint height increased from 2.98 ± 0.27 mm to 4.37 ± 0.49 mm (p < 0.001). At 3 months, bone fusion was achieved in 93.8% of patients. Clinical outcomes improved compared with preoperative values, including JOA score (8.44 ± 0.89 to 13.31 ± 1.20), VAS score (8.00 ± 0.73 to 2.25 ± 0.45), and NDI score (31.88 ± 1.93 to 12.88 ± 1.26).

conclusionThis study introduces a novel minimally invasive technique for managing atlantoaxial instability using uniportal endoscopic-assisted posterior fusion. The combination of direct endoscopic visualization, accurate screw-rod fixation, and controlled intra-articular bone grafting offers reliable joint stabilization with reduced tissue disruption. Clinical outcomes suggest this approach may facilitate rapid recovery and improved perioperative safety, offering a valuable addition to current surgical strategies for AAI/D.

Indexed as

Atlanto-Axial JointEndoscopyJoint InstabilitySpinal FusionAdultBone TransplantationFemaleHumansMaleMiddle AgedTreatment Outcomeatlantoaxial instabilityC1–C2 fixationendoscopic‐assisted fusionminimally invasive spine surgerytechnical innovation

Identifiers

PMID42266154
PMCPMC13399054

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.