Evidence map›Paper›PMID 42266249›Full record

ArticleFrontiers in cellular neuroscience2026

Combination drug therapy reduces iron accumulation and microglia-mediated pathologies in neonatal intraventricular hemorrhage: a biochemical and transcriptomic analysis.

Vanessa Castro Diaz, Michelle Sunshine, Furong Hu, Sohan Shah, Weihua Huang, Carl I Thompson, Michael S Wolin, Selvakumar Subbian, Edmund F LaGamma, Govindaiah Vinukonda

Abstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vanessa Castro DiazThe Regional Neonatal Center, Maria Fareri Children's Hospital at Westchester Medical Center, Division of Pediatric-Newborn Medicine, New York Medical College, Valhalla, NY, United States.
Michelle SunshineThe Regional Neonatal Center, Maria Fareri Children's Hospital at Westchester Medical Center, Division of Pediatric-Newborn Medicine, New York Medical College, Valhalla, NY, United States.
Furong HuDepartment of Pediatrics, New York Medical College, Valhalla, NY, United States.
Sohan ShahThe Regional Neonatal Center, Maria Fareri Children's Hospital at Westchester Medical Center, Division of Pediatric-Newborn Medicine, New York Medical College, Valhalla, NY, United States.
Weihua HuangDepartment of Pathology and Laboratory Medicine, Brody School of Medicine at East Carolina University, Grenville, NC, United States.
Carl I ThompsonDepartment of Cell and Molecular Physiology, New York Medical College, Valhalla, NY, United States.
Michael S WolinDepartment of Cell and Molecular Physiology, New York Medical College, Valhalla, NY, United States.
Selvakumar SubbianPublic Health Research Institute, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, United States.
Edmund F LaGammaThe Regional Neonatal Center, Maria Fareri Children's Hospital at Westchester Medical Center, Division of Pediatric-Newborn Medicine, New York Medical College, Valhalla, NY, United States.
Govindaiah VinukondaDepartment of Pediatrics, New York Medical College, Valhalla, NY, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study describes the distribution of non-reactive brain-resident microglia densely populated along the borders of the lateral ventricles and choroid plexus in premature rabbit pups during early forebrain development. Following intraventricular hemorrhage (IVH) injury, activated microglia expand by proliferation, and migrate deeper into parenchymal regions. During this process, activated microglia exhibit a disproportionate elevation of the proinflammatory microglia phenotype (M1 nomenclature) from the total IBA-1

Indexed as

brain injurycorona radiatacorpus callosumdeferoxamineferroptosisgene networksgerminal matrixintraventricular hemorrhage

Identifiers

PMID42266249
PMCPMC13243052

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.