Evidence map›Paper›PMID 42266716›Full record

ArticleFrontiers in neurorobotics2026

Interpretable side-aware kinematic-sEMG gait-state representations relevant to adaptive neurorobotic assistance after stroke: a public-dataset study.

Rocco Salvatore Calabrò, Andrea Calderone, Alessio Baricich, Andrea Santamato, Francesca Antonia Arcadi, Alessandro Marco De Nunzio, Angelo Quartarone

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Article in Frontiers in neurorobotics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Rocco Salvatore CalabròIRCCS Centro Neurolesi Bonino Pulejo, Messina, Italy.
Andrea CalderoneIRCCS Centro Neurolesi Bonino Pulejo, Messina, Italy.
Alessio BaricichDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.
Andrea SantamatoPhysical Medicine and Rehabilitative Unit-Riuniti Hospital, University of Foggia, Foggia, Italy.
Francesca Antonia ArcadiIRCCS Centro Neurolesi Bonino Pulejo, Messina, Italy.
Alessandro Marco De NunzioDepartment of Research and Development, LUNEX International University of Health, Differdange, Luxembourg.
Angelo QuartaroneIRCCS Centro Neurolesi Bonino Pulejo, Messina, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Adaptive lower-limb neurorobotics requires gaitd-state representations that preserve locomotor structure without reducing post-stroke walking to a single asymmetry score or opaque latent embedding. Because post-stroke gait is multimodal and side dependent, transparent side-aware representations may better support future adaptive-assistance design than modality-isolated summaries. Methods: This secondary analysis used a public multimodal gait dataset comprising 138 able-bodied adults and 50 adults with stroke. The analytic space was restricted to 11 waveform domains shared across public exports: four sagittal kinematic waveforms and seven repository-normalized surface electromyography waveforms, each represented by 1,001 time-normalized points. Stroke waveforms were organized into paretic, non-paretic, bilateral-mean, and side-difference views, with side difference defined as paretic minus non-paretic. Domain-view functional principal component analysis retained 90% cumulative variance, capped at three components per block; family-level reduction retained 90% variance, capped at eight components. Candidate Ward hierarchical and K-means solutions from two to five states were screened in kinematics-only, sEMG-only, fused, paretic-only, and erector-spinae-excluded spaces. Results: The retained fused side-aware solution organized the strict complete-case stroke cohort ( Conclusion: Public waveform exports supported an internally interpretable, side-aware multimodal representation of post-stroke gait relevant to neurorobotic state-representation design. This contribution remains exploratory and representational, not clinical, interventional, real-time, or controller-validating; for future studies, it should be interpreted as a hypothesis-generating framework.

Indexed as

adaptive gait assistancegait kinematicslatent state discoverymodel interpretabilitymultimodal representationneuroroboticspost-stroke gaitsurface electromyography

Identifiers

PMID42266716
PMCPMC13243435

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.