ReviewBiochemical Society transactions2026
The multifaceted roles of receptor tyrosine pseudokinases in cellular signalling.
Review in Biochemical Society transactions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Black Sheep: Pseudokinases Bucking the Trend to Reveal Non-Catalytic Kinase Functions.IUBMB life · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Receptor tyrosine pseudokinases comprise approximately 10% of the receptor tyrosine kinase family and lack phosphotransferase activity due to substitutions of essential catalytic residues within their kinase folds. This review critically examines the eight human receptor tyrosine pseudokinases: EphA10, EphB6, HER3, PTK7, ROR1, ROR2, RYK, and STYK1. By reconciling recent structural and functional data, we highlight the diverse non-catalytic mechanisms these pseudokinases employ in cellular communication. This comprehensive analysis provides insights into non-canonical signalling pathways and highlights potential for therapeutic opportunities in diseases associated with pseudokinase dysfunction.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.