Evidence map›Paper›PMID 42268343›Full record

ReviewApplied biochemistry and biotechnology2026

Green Nanomedicine from Eupatorium: Phytochemical-Driven Synthesis of Therapeutic Nanoparticles for Biomedical Applications.

Sorimuthu Revathi, Nibedita Dey, Muruganantham Bharathi, Ragothaman Prathiviraj, Lalitha Gnanasekaran, Shanmugapriya D, Arpita Roy, Rajaram Rajmohan, Thanigaivel Sundaram

Abstract readReview
PubMed Publisher
In one paragraph

Review in Applied biochemistry and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sorimuthu RevathiDepartment of Emergency Medicine, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Thandalam, Chennai, India.
Nibedita DeyDepartment of Medical Biotechnology, Saveetha School of Engineering, SIMATS College, Thandalam, Chennai, India. nibeditadey.sse@saveetha.com.
Muruganantham BharathiCentre for Bioinformatics, Department of Biochemistry, Karpagam Academy of Higher Education, Coimbatore, 641021, Tamilnadu, India.
Ragothaman PrathivirajDivision of Bioinformatics and Systems Biology, Department of Biosciences, Rajagiri College of Social Sciences (Autonomous), Rajagiri P.O, Kalamassery, Kochi, 683104, India.
Lalitha GnanasekaranInternational Center of Nanotechnology and Functional Materials, Instituto de Alta Investigación, Universidad de Tarapacá, Arica, 1000000, Chile.
Shanmugapriya DVicerrectoría de Investigación y Postgrado, Universidad de La Serena, La Serena, 1700000, Chile.
Arpita RoyCentre for Research Impact & Outcome, Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura, 140401, Punjab, India.
Rajaram RajmohanSchool of Chemical Engineering, Yeungnam University, Gyeongsan, 38541, Republic of Korea. rajmohanau@yu.ac.kr.
Thanigaivel SundaramDepartment of Biotechnology, Faculty of Science and Humanities, SRM Institute of Science and Technology, Kattankulathur, Chennai, 603203, India. thanigaivel092@gmail.com.ORCID http://orcid.org/0000-0002-8698-3858

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The review discusses the evolution of the genus Eupatorium from a traditional herbal medicine to a significant drug in green sustainable nanomedicine, addressing to the demand for focused scientific bridge between its phytochemistry and nanotechnology. The synthesis of Eupatorium-mediated nanoparticles is determined by secondary metabolites, specifically flavonoids such as eupafolin, as well as phenolic acids and terpenoids. The hydroxyl (-OH) and carbonyl (C = O) functional groups of these compounds contribute to the bioconjugation of metal ions that turn into valuable nanoparticles, while they also act as capping agents to prevent aggregation, typically producing particles on the scale of 10-100 nm. Quantitative data evidence showed enhanced effectiveness of these nano formulations compared to crude extracts; antimicrobial zones of inhibition reaching 9-20 mm against pathogens such as E. coli and S. aureus, additionally antiviral efficacy against clinical viruses induced by E. perfoliatum have been reported in the range 59.59% to 72.78% .In addition, specific compounds such as eupalinolide demonstrate potent cytotoxicity with IC

Indexed as

EupatoriumGreen Chemistry TechnologyNanomedicineNanoparticlesPhytochemicalsAnti-Infective AgentsHumansPlant ExtractsAnti-Infective AgentsPhytochemicalsPlant ExtractsAntibacterialEupalinolideEupatoriumMedicine, pharmacological mechanismSustainable nanoparticles

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.