Evidence mapPaperPMID 42272175Full record

ReviewAngewandte Chemie (International ed. in English)2026

Toward Chromoselective Transformations in Biological Systems: Perspectives and Challenges.

Nadja A Simeth

Abstract readReview
In one paragraph

Review in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Nadja A SimethDepartment of Chemistry, Institute For Organic and Biomolecular Chemistry, University of Göttingen, Göttingen, Germany.ORCID https://orcid.org/0000-0001-8130-883X

Funding

Deutsche Forschungsgemeinschaft EXC2067/1-390729940Vetenskapsrådet 2023-04088
6 · The paper itself

Abstract

Addressing small-molecule chromophores with bioactive properties has been established as an effective means of controlling biological systems for several decades. However, the complexity of in vitro and especially in vivo systems cannot be matched by a single wavelength of light (de)activating one kind of chromophore. Consequently, developing methods to combine and individually control multiple chromophores within the same system is of high importance. An increasing number of strategies have become available relying on the chromoselective transformation of small molecules. This article features the chromoselective control of photoswitches, photoclick chemistry, and photocages, and highlights perspectives and future challenges to be overcome in the context of biological systems.

Indexed as

Chromophore-Assisted Light InactivationLightPhotochemical ProcessesStereoisomerismchemical biologyphotocagesphotochemistryphotoswitches

Identifiers

PMID42272175
PMCPMC13411233

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.