Evidence mapPaperPMID 42272995Full record

ReviewAlcohol research : current reviews2026

Leveraging Machine Learning to Advance Alcohol Research: Current Applications, Challenges, and Opportunities.

Qingyu Zhao, Kilian M Pohl

Abstract readReview
In one paragraph

Review in Alcohol research : current reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Qingyu ZhaoDepartment of Radiology, Weill Cornell Medicine, New York, New York.ORCID 0000-0002-6368-0889
Kilian M PohlDepartment of Psychiatry & Behavioral Sciences, Stanford University, Stanford, California.ORCID 0000-0001-5416-5159

Funding

CEREBELLAR STRUCTURE AND FUNCTION IN ALCOHOLISMR01AA010723 · STANFORD UNIVERSITY · 1996 to 2025
$3.5M
NCANDA: Data Analysis ResourceU24AA021697 · STANFORD UNIVERSITY · 2025 to 2025
$1.1M
Tracking HIV Infection & Alcohol Abuse CNS Comorbidity with NeuroimagingR01AA017347 · SRI INTERNATIONAL · 2025 to 2025
$901k
CNS DEFICITS: INTERACTION OF AGE AND ALCOHOLISMR01AA005965 · STANFORD UNIVERSITY · 1985 to 2025
$826k
Interpretable Deep Forecasting of Hazardous Substance Use during High SchoolR01DA057567 · STANFORD UNIVERSITY · 2025 to 2025
$456k
Longitudinal Analysis of Diffusion Tensor Imaging to Discover Adolescent Alcohol Use EffectR00AA028840 · WEILL MEDICAL COLL OF CORNELL UNIV · 2025 to 2025
$249k
NIAAA NIH HHS R00 AA028840NIAAA NIH HHS R01 AA005965NIAAA NIH HHS R01 AA010723NIAAA NIH HHS R01 AA017347NIAAA NIH HHS U24 AA021697NIDA NIH HHS R01 DA057567
6 · The paper itself

Abstract

purposeThe review surveys the type of machine learning approaches currently used in the alcohol literature, reviews challenges in applying machine learning tools to alcohol data, and explores how overcoming these challenges could advance personalized medicine for alcohol use disorder (AUD). SEARCH

methodsThe authors conducted a search of publications on PubMed, ScienceDirect, and EBSCO Academic Search Premier published from 2015 to April 15, 2025, for articles that used machine learning to analyze alcohol-related outcomes. Search terms were ("drinking" OR "alcohol") AND ("machine learning" OR "deep learning" OR "predict" OR "classify") in the title or abstract. SEARCH

resultsThe search returned 2,618 manuscripts. Keeping those that predicted alcohol-related outcomes and excluding those that merely used alcohol as a predictor for other outcomes reduced the selection to 567 manuscripts. A final manual selection resulted in 110 original peer-reviewed human research studies that primarily analyzed alcohol consumption behaviors and tested their models on data that they were not trained on. DISCUSSION AND

conclusionsPredictions focused on alcohol consumption or AUD diagnosis in cohorts with a mean age of 50 years or younger (i.e., when long-term drinking behaviors are being or have been established). Most studies confined the data-driven searches to a single modality and relied on conventional machine learning approaches, which tended to produce accurate and transparent predictions on the relatively small datasets typically collected by AUD studies. The small number of available samples was the most common limitation mentioned by the reviewed articles. Investigators also wished for machine learning models to provide insights about causality. Gaining these insights will be essential to improve diagnosis and treatment of AUD, for which the field must foster multidisciplinary research teams to build rigorous and trustworthy machine learning models and quantitative benchmarks that can capture the multifaceted nature of alcohol use and its comorbidities.

Indexed as

Alcohol DrinkingAlcoholismBiomedical ResearchMachine LearningData AnalyticsHumansPredictive Learning Modelsalcoholmachine learningpredictive

Identifiers

PMID42272995
PMCPMC13249275

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.