Evidence map›Paper›PMID 42273000›Full record

ReviewTouchREVIEWS in endocrinology2026

Burosumab for X-linked Hypophosphataemia and Tumour-induced Osteomalacia in Adults.

Simon Black, Richard Keen, Judith Bubbear

Abstract readReview
In one paragraph

Review in TouchREVIEWS in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Simon BlackMetabolic Bone Disease Centre, Royal National Orthopaedic Hospital, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex, UK.
Richard KeenMetabolic Bone Disease Centre, Royal National Orthopaedic Hospital, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex, UK.
Judith BubbearMetabolic Bone Disease Centre, Royal National Orthopaedic Hospital, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, Middlesex, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

X-linked hypophosphataemia and tumour-induced osteomalacia are rare, distinct metabolic conditions that can affect both children and adults, and result in elevated fibroblast growth factor-23 levels and subsequent low phosphate levels. This leads to severe musculoskeletal symptoms and complications, and these conditions carry significant disease burden and high levels of morbidity. In this article, we examine the conditions and analyse the use of burosumab, a recently developed monoclonal antibody treatment, in the care of adults with these conditions.

Indexed as

Burosumabfibroblast growth factor (FGF)-23hypophosphataemiaosteomalaciaricketstumour-induced osteomalaciaX-linked hypophosphataemia

Identifiers

PMID42273000
PMCPMC13249216

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.