ReviewJournal of immunology research2026
The Role of BMAL1 in Regulating Circadian Rhythms During Airway Remodeling in Asthma.
Review in Journal of immunology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The Role of BMAL1 in Regulating Circadian Rhythms During Airway Remodeling in Asthma.Journal of immunology research · 2026Review
- Natural bioactive compounds targeting the macrophage clock in asthma: evidence, challenges, and perspectives.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Asthma is a chronic respiratory disease characterized by airway inflammation, hyperresponsiveness, and remodeling. The circadian clock governs natural 24 h biological rhythms, encompassing physiological, metabolic, and hormonal fluctuations. It regulates key physiological processes like sleep, activity, and feeding, playing a crucial role in maintaining normal respiratory function. However, the mechanisms underlying asthma airway remodeling and its relationship with circadian clock genes remain incompletely understood. Brain and muscle arnt-like 1 (BMAL1), a core circadian clock gene, plays a significant role in the proliferation and differentiation of airway stem cells. This review summarizes recent advances in clinically relevant asthma research, including the role of airway remodeling in disease progression. It then focuses on unresolved scientific questions regarding the function of the BMAL1 gene in asthma pathogenesis, aiming to contribute to the future development of metabolic rhythm-based strategies as novel targets for asthma diagnosis and treatment.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.