Evidence map›Paper›PMID 42274515›Full record

ReviewBiology2026

Epithelial Sodium Channel in the Respiratory System: A Bibliometric Review of Recent Studies.

Yunmei Fu, Yifan Yao, Hong-Long Ji, Hongguang Nie

Abstract readReview
In one paragraph

Review in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yunmei FuDepartment of Stem Cells and Regenerative Medicine, College of Basic Medical Science, China Medical University, Shenyang 110122, China.
Yifan YaoDepartment of Pharmaceutical Toxicology, School of Pharmacy, China Medical University, Shenyang 110122, China.
Hong-Long JiDepartment of Surgery, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.
Hongguang NieDepartment of Stem Cells and Regenerative Medicine, College of Basic Medical Science, China Medical University, Shenyang 110122, China.ORCID 0000-0002-9973-6354

Funding

National Natural Science Foundation of China 82170093
6 · The paper itself

Abstract

Inhibiting epithelial sodium channel (ENaC) provides clinical benefit in cystic fibrosis treatment, whereas activated alveolar ENaC attenuates acute lung injury/acute respiratory distress syndrome. However, seldom bibliometric analysis of respiratory ENaC systematically evaluates hotspots and trends in ion transport, as well as providing few overviews for researchers. This review aims to provide a comprehensive overview of respiratory ENaC over the past 40 years, identifying the research frontier and topic evolution. Searching the literature in Science Citation Index Expanded from Web of Science (WOS) and PubMed, a total of 1634 publications in 409 journals, authored by 5457 researchers from 60 countries/regions, were analyzed by CiteSpace, VOSviewer, and sciMAT software. The earliest highly cited article, titled 'Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770', had accumulated 1011 citations. The most prolific author, country, and journal were MA Mall, USA, and

Indexed as

acute lung injurybibliometric analysisepithelial sodium channelinflammatory responsespathophysiology

Identifiers

PMID42274515
PMCPMC13256070

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.