Sustained CREB Phosphorylation Is Associated with Neuritogenic Prostanoid Signaling in NSC-34 Cells.

Koume Nagayama, Hiroshi Nango, Komugi Tsuruta, Hiroko Miyagishi, Yasuhiro Kosuge

Abstract read

In one paragraph

Article in Cells, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Koume NagayamaLaboratory of Pharmacology, School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba 274-8555, Japan.

Hiroshi NangoLaboratory of Pharmacology, School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba 274-8555, Japan.ORCID 0000-0002-8271-9937

Komugi TsurutaLaboratory of Pharmacology, School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba 274-8555, Japan.ORCID 0009-0001-9920-7874

Hiroko MiyagishiLaboratory of Pharmacology, School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba 274-8555, Japan.ORCID 0000-0002-3909-867X

Yasuhiro KosugeLaboratory of Pharmacology, School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba 274-8555, Japan.ORCID 0000-0002-7513-5132

Funding

Japan Society for the Promotion of Science 24K23279School of Pharmacy, Nihon University A grant to encourage and promote research projects for graduate students in the School of Pharmacy, Nihon UniversityThe Yukihiko Miyata Memorial Trust for ALS Research N/A

6 · The paper itself

Abstract

Neuritogenesis is essential for neuronal development and circuit formation. Although cAMP signaling downstream of Gs-coupled receptors is considered pro-neuritogenic, activation of these Gs-coupled receptors can produce divergent cellular outcomes. We previously showed that prostaglandin E

Indexed as

Cyclic AMP Response Element-Binding ProteinNeuritesProstaglandinsSignal TransductionAlprostadilAnimalsCell LineCyclic AMPCyclic AMP-Dependent Protein KinasesDinoprostoneEpoprostenolMicePhosphorylationReceptors, Prostaglandin E, EP2 SubtypeAlprostadilberaprostbutaprostCyclic AMPCyclic AMP-Dependent Protein KinasesCyclic AMP Response Element-Binding ProteinDinoprostoneEpoprostenolProstaglandinsReceptors, Prostaglandin E, EP2 SubtypecAMPcAMP response element binding proteinneurite outgrowthNSC-34 cellprostaglandinprotein kinase A

Identifiers

PMID42274597

DOI10.3390/cells15111004

PMCPMC13257260

What Socratic holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.