Evidence map›Paper›PMID 42275555›Full record

ArticleChemistry & biodiversity2026

Phytochemical Profiling, Antiplatelet Potential, and Cytotoxic Assessment of Thymelaea tartonraira Aerial Part Essential Oil: In Vitro and In Silico Studies.

Siwar Soltani, Asma Haffouz, Imed Koubaa, Ali Gargouri, Amira Jerbi, Ikram Ben Amor, Jalel Gargouri, Basma HadjKacem, Noureddine Allouche

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Siwar SoltaniLaboratory of Organic Chemistry LR17ES08, Natural Substances Team, Faculty of Sciences of Sfax, University of Sfax, Sfax, Tunisia.
Asma HaffouzLaboratory of Molecular Biotechnology of Eukaryotes, Centre of Biotechnology of Sfax, University of Sfax, Sfax, Tunisia.
Imed KoubaaLaboratory of Organic Chemistry LR17ES08, Natural Substances Team, Faculty of Sciences of Sfax, University of Sfax, Sfax, Tunisia.
Ali GargouriLaboratory of Molecular Biotechnology of Eukaryotes, Centre of Biotechnology of Sfax, University of Sfax, Sfax, Tunisia.
Amira JerbiLaboratory of Hematology, Medical Faculty of Sfax. University of Sfax, Sfax, Tunisia.
Ikram Ben AmorLaboratory of Hematology, Medical Faculty of Sfax. University of Sfax, Sfax, Tunisia.
Jalel GargouriLaboratory of Hematology, Medical Faculty of Sfax. University of Sfax, Sfax, Tunisia.
Basma HadjKacemLaboratory of Molecular Biotechnology of Eukaryotes, Centre of Biotechnology of Sfax, University of Sfax, Sfax, Tunisia.
Noureddine AlloucheLaboratory of Organic Chemistry LR17ES08, Natural Substances Team, Faculty of Sciences of Sfax, University of Sfax, Sfax, Tunisia.

Funding

Centre de Biotechnologie de SfaxMinistry of Higher Education, Scientific Research and Technologies of Tunisia
6 · The paper itself

Abstract

This study evaluates the antiplatelet potential of Thymelaea tartonraira essential oil, obtained from aerial parts by hydrodistillation. GC-MS analysis identified 43 compounds, with phenethyl alcohol (25.69%), eugenol (12.42%), and carvacrol (6.41%) as major constituents. In vitro platelet aggregation assays showed significant inhibition, with IC

Indexed as

Oils, VolatilePhytochemicalsPlatelet Aggregation InhibitorsBlood PlateletsCell SurvivalCyclooxygenase 1Dose-Response Relationship, DrugErythrocytesHEK293 CellsHumansMolecular Docking SimulationPlant Components, AerialPlatelet AggregationReceptors, Purinergic P2Y12Structure-Activity RelationshipCyclooxygenase 1Oils, VolatilePhytochemicalsPlatelet Aggregation InhibitorsReceptors, Purinergic P2Y12anti‐platelet activitycarvacroleugenolphenethyl alcoholThymelaea tartonraira

Identifiers

PMID42275555
PMCPMC13258193

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.