ArticleJournal of magnetic resonance imaging : JMRI2026
Association Between HIV Infection Duration and Left Ventricular Concentric Remodeling and Myocardial Fibrosis: A Cross-Sectional Study Using Cardiac MRI.
Article in Journal of magnetic resonance imaging : JMRI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Editorial for "Association Between HIV Infection Duration and Left Ventricular Concentric Remodeling and Myocardial Fibrosis: A Cross-Sectional Study Using Cardiac MRI".Journal of magnetic resonance imaging : JMRI · 2026Article
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Authors and funding
6 authors.
Funding
Abstract
backgroundAntiretroviral therapy has transformed HIV into a chronic condition, yet cardiac injury remains a major issue. PURPOSE: To assess the ability of cardiac MR imaging markers to predict cardiac injury and disease progression in HIV-infected individuals. STUDY TYPE: Prospective. SUBJECTS: Eighty-three HIV-infected participants (short-duration infection < 5 years, n = 43; long-duration ≥ 5 years, n = 40) and 34 matched HIV-negative controls. FIELD STRENGTH/SEQUENCE: 1.5 T; SSFP cine and MOLLI sequences. ASSESSMENT: Left ventricular (LV) end diastolic volume indexed to body surface area (LVEDVi), ejection fraction (LVEF), mass (LVM), myocardial mass-to-volume ratio (MVR), and global strains were determined from SSFP cine data. Extracellular volume (ECV) and myocardial extracellular matrix volume index (ECMVi) were determined from pre- and post-contrast myocardial T1 values. STATISTICAL TESTS: ANOVA, Kruskal-Wallis, post hoc tests, correlation, and multivariable logistic regression; p < 0.05 indicated statistical significance.
resultsBoth the HIV groups showed significantly elevated ECV (short: median 28.02 [25.40-31.86]%; long: median 28.18 [24.40-37.99]% vs. 25.07% ± 5.61%) and myocardial native T1 (1863.35 ± 300.29 ms; median 1963.00 [1807.00, 2072.25] ms vs. median 1734 [1309.75-1981.50] ms) compared to controls. The long-duration group exhibited significantly higher ECMVi (14.73 ± 4.59 mL/m
conclusionECV, myocardial native T1, and FBG can predict short-duration HIV infection, while a multimodal model (LVEDVi, ECMVi, and FBG)stratifies duration. However, prospective validation is necessary. EVIDENCE LEVEL: 2. TECHNICAL EFFICACY: Stage 3.
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