Evidence map›Paper›PMID 42278113›Full record

ArticleAnimals : an open access journal from MDPI2026

Behavioral Convergence with Physiological Divergence: Sex Differences in Hormones but Not Social Behavior in Beagle Dogs.

Yu-Huan Xiao, Zi-Hua Zhao, Xue-Yan Jiang, Jun Zhang, Wen-Bing He, Rui Dong, Xue-Ting Zhang, Li-Xian Tao, Jun-Lv Ma, Jin-Xiu Li and 1 more

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yu-Huan XiaoState Key Laboratory of Genetic Evolution & Animal Models, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650201, China.
Zi-Hua ZhaoBio-X Center for Interdisciplinary Innovation, Yunnan University, Kunming 650500, China.
Xue-Yan JiangState Key Laboratory of Genetic Evolution & Animal Models, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650201, China.
Jun ZhangBio-X Center for Interdisciplinary Innovation, Yunnan University, Kunming 650500, China.
Wen-Bing HeState Key Laboratory of Genetic Evolution & Animal Models, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650201, China.
Rui DongState Key Laboratory of Genetic Evolution & Animal Models, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650201, China.
Xue-Ting ZhangState Key Laboratory of Genetic Evolution & Animal Models, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650201, China.
Li-Xian TaoState Key Laboratory of Genetic Evolution & Animal Models, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650201, China.
Jun-Lv MaState Key Laboratory of Genetic Evolution & Animal Models, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650201, China.
Jin-Xiu LiState Key Laboratory of Genetic Evolution & Animal Models, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650201, China.
Ya-Ping ZhangState Key Laboratory of Genetic Evolution & Animal Models, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650201, China.ORCID 0000-0002-5401-1114

Funding

Major Science and Technology Program of Yunnan 202502AU100002National Natural Science Foundation of China 32100411National Natural Science Foundation of China 32388102the STI2030-Major Projects 2021ZD0203900
6 · The paper itself

Abstract

The "experimenter gender effect" is a pervasive confound in rodent behavioral neuroscience: the sex of the human handler alters stress, social, and pharmacological responses via olfactory cues and conserved neural circuits. Whether this effect extends to dog-a species co-domesticated with humans for over 15,000 years-has never been systematically tested. Here, we examined sex-biased social preferences in Beagle dogs during both intra- and cross-species interactions, and asked whether baseline neuroendocrine states predict such preferences. Thirty-four adult Beagles (17 males, 17 females) from a standardized laboratory colony underwent social interaction tests with same and opposite-sex conspecifics and with male and female experimenters. Baseline plasma corticosterone, serotonin (5-HT), and dopamine were measured by ELISA. Results indicated that Beagles did not exhibit significant sex-based preferences for either gender of conspecifics or human experimenters in either dog-dog or human-dog social interaction tests (all

Indexed as

Beagle dogsdomesticationexperimenter gender effecthormonesSocial interactions

Identifiers

PMID42278113
PMCPMC13255820

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.