ArticleAnimals : an open access journal from MDPI2026
Alterations in Blood Markers, Rumen Fermentation, and Microbiota Due to Heat Stress in Holstein Cows During the Dry Period and Early Lactation.
Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
In this study, physiological and microbial responses under heat stress conditions were evaluated by analyzing blood biochemical parameters, rumen fermentation characteristics, and rumen microbiome (bacterial community composition) in Holstein dairy cows during the dry period and early lactation under summer conditions in Korea. Fourteen cows were observed during the hot summer month (from the first to the third week of August), with the temperature-humidity index (THI) recorded in the barns during the dry and early lactation periods being 80.80 and 81.66, respectively. Blood and rumen fluid samples were collected to evaluate physiological responses and changes in blood parameters, rumen fermentation, and rumen microbial composition. Blood analysis revealed significant variations between the two stages. Early lactating cows exhibited lower glucose, blood urea nitrogen, and cholesterol levels but higher ketone and aspartate aminotransferase levels, indicating increased energy demands and protein metabolism. A complete blood count showed reduced red blood cell count, hematocrit, and hemoglobin levels during the early lactation period, whereas white blood cell counts increased. The levels of heat shock proteins (HSPs), such as HSP27, HSP70, and HSP90, also differed significantly. Rumen fermentation analysis revealed lower ammonia nitrogen concentrations but significantly higher propionate and total volatile fatty acid concentrations during the early lactation period, indicating adaptive changes in rumen function. Rumen microbial analysis revealed significant differences in bacterial diversity and composition. Early lactation cows exhibited relatively high abundances of Bacteroidota and
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