ArticleInternational journal of molecular sciences2026
Inflammasome Gene Polymorphisms (NLRP3 and NLRC4) and Vitamin D Status in Patients with Multiple Sclerosis.
Concetta Scazzone, Luisa Agnello, Caterina Maria Gambino, Chiara Bellia, Giuseppe Salemi, Anna Masucci, Sabrina Novara, Marcello Ciaccio
Abstract read
In one paragraphArticle in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
8 authors.
Concetta ScazzoneDepartment of Biomedicine, Neurosciences and Advanced Diagnostics, Institute of Clinical Biochemistry, Clinical Molecular Medicine, and Clinical Laboratory Medicine, University of Palermo, 90127 Palermo, Italy.ORCID 0000-0001-7424-8066 Luisa AgnelloDepartment of Biomedicine, Neurosciences and Advanced Diagnostics, Institute of Clinical Biochemistry, Clinical Molecular Medicine, and Clinical Laboratory Medicine, University of Palermo, 90127 Palermo, Italy.
Caterina Maria GambinoDepartment of Biomedicine, Neurosciences and Advanced Diagnostics, Institute of Clinical Biochemistry, Clinical Molecular Medicine, and Clinical Laboratory Medicine, University of Palermo, 90127 Palermo, Italy.
Chiara BelliaDepartment of Biomedicine, Neurosciences and Advanced Diagnostics, Institute of Clinical Biochemistry, Clinical Molecular Medicine, and Clinical Laboratory Medicine, University of Palermo, 90127 Palermo, Italy.ORCID 0000-0003-0611-9363 Giuseppe SalemiUnit of Neurology, Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, 90127 Palermo, Italy.ORCID 0000-0002-3756-4323 Anna MasucciDepartment of Biomedicine, Neurosciences and Advanced Diagnostics, Institute of Clinical Biochemistry, Clinical Molecular Medicine, and Clinical Laboratory Medicine, University of Palermo, 90127 Palermo, Italy.
Sabrina NovaraDepartment of Biomedicine, Neurosciences and Advanced Diagnostics, Institute of Clinical Biochemistry, Clinical Molecular Medicine, and Clinical Laboratory Medicine, University of Palermo, 90127 Palermo, Italy.
Marcello CiaccioDepartment of Biomedicine, Neurosciences and Advanced Diagnostics, Institute of Clinical Biochemistry, Clinical Molecular Medicine, and Clinical Laboratory Medicine, University of Palermo, 90127 Palermo, Italy.ORCID 0000-0001-6120-9041 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Multiple Sclerosis (MS) is a neuroinflammatory disorder in which genetic and environmental factors contribute to disease onset. Evidence implicates the inflammasome pathway in MS pathophysiology. However, the interaction between inflammasome-related genetic variants and 25-OH-vitamin D
Indexed as
Calcium-Binding ProteinsCARD Signaling Adaptor ProteinsInflammasomesMultiple SclerosisNLR Family, Pyrin Domain-Containing 3 ProteinPolymorphism, Single NucleotideVitamin DAdultCase-Control StudiesFemaleGenetic Predisposition to DiseaseGenotypeHumansMaleMiddle AgedCalcium-Binding ProteinsCARD Signaling Adaptor ProteinsInflammasomesNLRC4 protein, humanNLR Family, Pyrin Domain-Containing 3 ProteinNLRP3 protein, humanVitamin Dinflammasomesmultiple sclerosisneuroinflammatory diseasespyrin domain-containing 3 proteinvitamin D
Identifiers
PMID42278212
PMCPMC13256696
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