Evidence map›Paper›PMID 42278380›Full record

ArticleInternational journal of molecular sciences2026

Adverse Hemodynamics in Acute Heart Failure Patients Are Associated with Skeletal Muscle Stress Biomarkers.

Kamil A Kobak, Monika Kasztura, Krystian Josiak, Robert Zymliński, Natalia Świątoniowska-Lonc, Waldemar Banasiak, Kinga Węgrzynowska-Teodorczyk

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kamil A KobakAging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104, USA.ORCID 0000-0003-1804-6333
Monika KaszturaDepartment of Food Hygiene and Consumer Health Protection, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw, Poland.
Krystian JosiakDepartment of Cardiology, Center for Heart Diseases, 4th Military Hospital, 50-981 Wroclaw, Poland.
Robert ZymlińskiInstitute of Heart Diseases, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0003-1483-7381
Natalia Świątoniowska-LoncDepartment of Cardiology, Center for Heart Diseases, 4th Military Hospital, 50-981 Wroclaw, Poland.ORCID 0000-0003-4211-9205
Waldemar BanasiakDepartment of Cardiology, Center for Heart Diseases, 4th Military Hospital, 50-981 Wroclaw, Poland.
Kinga Węgrzynowska-TeodorczykDepartment of Cardiology, Center for Heart Diseases, 4th Military Hospital, 50-981 Wroclaw, Poland.ORCID 0000-0001-9189-748X

Funding

American Heart Association 25CDA1432894National Science Centre UMO-2013/11/D/NZ7/00922
6 · The paper itself

Abstract

Acute heart failure (AHF) causes abrupt hemodynamic disturbances, including reduced forward flow and venous congestion, which may extend beyond the heart and contribute to peripheral organ stress. Skeletal muscle may be particularly vulnerable to these changes, but the relationship between acute hemodynamic status and circulating markers of skeletal muscle stress and regulation remains unclear. We prospectively enrolled 35 men hospitalized with AHF and non-invasively assessed their cardiac index (CI) by impedance cardiography and right atrial pressure (RAP) by echocardiography. Plasma carbonic anhydrase III (CA3), creatine kinase-MM (CK-MM), lactate, myostatin, and follistatin were measured at admission, discharge, and 30 days after discharge. Patients were analyzed according to low CI, defined as CI < 2.2 L·min

Indexed as

BiomarkersHeart FailureHemodynamicsMuscle, SkeletalAcute DiseaseAgedHumansMaleMiddle AgedProspective StudiesBiomarkersacute heart failurebiomarkershemodynamicsskeletal muscle

Identifiers

PMID42278380
PMCPMC13256547

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.