ArticleInternational journal of molecular sciences2026
Pharmacological Ascorbate Restrains Epithelial-Mesenchymal Transition and Invasion in Glioblastoma Cells via Extracellular H
Onsurang Wattanathamsan, Naphat Chantaravisoot, Rungnapa Bootsri, Nuttiya Kalpongnukul, Napatsakon Youngsanbhu, Claudia R Oliva, Corinne E Griguer, Visarut Buranasudja
Abstract read
In one paragraphArticle in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
8 authors.
Onsurang WattanathamsanDepartment of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0009-0008-2208-0546 Naphat ChantaravisootDepartment of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0003-3946-1798 Rungnapa BootsriDepartment of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Nuttiya KalpongnukulCenter of Excellence in Systems Biology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Napatsakon YoungsanbhuDepartment of Biochemistry, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
Claudia R OlivaFree Radical and Radiation Biology Program, Department of Radiation Oncology, The University of Iowa, Iowa City, IA 52242, USA.
Corinne E GriguerFree Radical and Radiation Biology Program, Department of Radiation Oncology, The University of Iowa, Iowa City, IA 52242, USA.
Visarut BuranasudjaDepartment of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0002-3582-5980 Funding
Chulalongkorn University 3320250014ANational Research Council of Thailand N42A680085Thailand Science Research and Innovation HEA_FF_69_060_3300_008
6 · The paper itselfAbstract
Glioblastoma (GBM) is highly invasive, and diffuse tumor cell migration into surrounding brain tissue remains a major obstacle to durable therapeutic control. Pharmacological ascorbate (P-AscH
Indexed as
Ascorbic AcidBrain NeoplasmsEpithelial-Mesenchymal TransitionGlioblastomaHydrogen PeroxideCell Line, TumorCell MovementGene Expression Regulation, NeoplasticHumansNeoplasm InvasivenessSignal TransductionTOR Serine-Threonine KinasesAscorbic AcidHydrogen PeroxideTOR Serine-Threonine Kinasescancer therapyepithelial–mesenchymal transitionglioblastomahydrogen peroxideinvasionmigrationoxidative stresspharmacological ascorbatepro-oxidantvitamin C
Identifiers
PMID42278490
PMCPMC13257296
What Socratic holds
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