Evidence map›Paper›PMID 42279078›Full record

ReviewJournal of clinical medicine2026

Efficacy and Safety of Treatments for Paroxysmal Nocturnal Hemoglobinuria: A Systematic Literature Review.

Shreyans Gandhi, Isobel Munro, Victoria Shodimu, Neil Webb, Katharina Pannagl, Anggie Wiyani, Maria-Magdalena Balp

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shreyans GandhiDepartment of Haematological Medicine, King's College Hospital NHS Foundation Trust, London SE5 9RS, UK.ORCID 0000-0003-3532-231X
Isobel MunroSource Health Economics, London WC1V 7AA, UK.
Victoria ShodimuSource Health Economics, London WC1V 7AA, UK.ORCID 0009-0006-8323-0734
Neil WebbSource Health Economics, London WC1V 7AA, UK.ORCID 0000-0001-8390-0837
Katharina PannaglNovartis Pharmaceuticals UK Ltd., London W12 7FQ, UK.ORCID 0009-0002-2505-1405
Anggie WiyaniNovartis Pharmaceuticals UK Ltd., London W12 7FQ, UK.ORCID 0000-0002-5203-9797
Maria-Magdalena BalpNovartis Pharma AG, 4056 Basel, Switzerland.ORCID 0000-0002-8612-7680

Funding

Novartis Pharma AG N/A
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

complement 3complement 5complement factor Bcomplement factor Dcomplement inhibitorsparoxysmal nocturnal hemoglobinuriasafetysystematic reviewtreatment efficacy

Identifiers

PMID42279078
PMCPMC13258451

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.