Evidence map›Paper›PMID 42279452›Full record

ReviewDiagnostics (Basel, Switzerland)2026

Microbiomics: Novel Biomarkers of Colorectal Cancer Diagnosis and Prognosis.

Lielong Yang, Wenjian Meng, Tinghan Yang, Yuzhou Zhu, Ziqiang Wang

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lielong YangColorectal Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Wenjian MengColorectal Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Tinghan YangColorectal Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Yuzhou ZhuColorectal Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.
Ziqiang WangColorectal Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0000-0002-2874-1535

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With colorectal cancer (CRC) accounting for over 1.9 million new cases and 930,000 deaths globally in 2020, there is a critical need for innovative indicators to forecast disease advancement and therapeutic outcomes. The gut microbiome has emerged as a fertile area for discovering such diagnostic and prognostic signals. This narrative review collected current evidence on intestinal microorganisms and their metabolic products as candidate markers for CRC control. Intestinal communities influence malignancy through diverse mechanisms, including metabolic shifts, immune modulation, inflammation, proliferation/apoptosis regulation, genotoxicity, and mucosal barrier disruption. Pathogenic species, such as

Indexed as

biomarkercolorectal cancerdiagnosisFusobacterium nucleatumgut microbiomeimmunotherapyprognosis

Identifiers

PMID42279452
PMCPMC13257310

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.