ArticleMolecules (Basel, Switzerland)2026
Effects of Cardiomyopathic Mutations on the Cytoplasmic Tropomyosin Isoform Tpm1.7.
Svetlana G Roman, Salavat R Nabiev, Anastasia M Kochurova, Galina V Kopylova, Julia Y Antonets, Sergey Y Kleymenov, Valeriya V Mikhaylova, Daniil V Shchepkin, Alexander M Matyushenko, Victoria V Nefedova
Abstract read
In one paragraphArticle in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
10 authors.
Svetlana G RomanResearch Centre of Biotechnology, Russian Academy of Sciences, 119071 Moscow, Russia.ORCID 0000-0001-7926-9173 Salavat R NabievInstitute of Immunology and Physiology, Ural Branch of Russian Academy of Sciences, 620049 Yekaterinburg, Russia.ORCID 0000-0001-9095-6775 Anastasia M KochurovaInstitute of Immunology and Physiology, Ural Branch of Russian Academy of Sciences, 620049 Yekaterinburg, Russia.ORCID 0000-0002-5583-5342 Galina V KopylovaInstitute of Immunology and Physiology, Ural Branch of Russian Academy of Sciences, 620049 Yekaterinburg, Russia.ORCID 0000-0003-2976-2108 Julia Y AntonetsInstitute of Immunology and Physiology, Ural Branch of Russian Academy of Sciences, 620049 Yekaterinburg, Russia.ORCID 0009-0006-6418-8980 Sergey Y KleymenovResearch Centre of Biotechnology, Russian Academy of Sciences, 119071 Moscow, Russia.ORCID 0000-0001-5085-0327 Valeriya V MikhaylovaResearch Centre of Biotechnology, Russian Academy of Sciences, 119071 Moscow, Russia.ORCID 0000-0002-2148-1697 Daniil V ShchepkinInstitute of Immunology and Physiology, Ural Branch of Russian Academy of Sciences, 620049 Yekaterinburg, Russia.ORCID 0000-0001-6660-4673 Alexander M MatyushenkoResearch Centre of Biotechnology, Russian Academy of Sciences, 119071 Moscow, Russia.ORCID 0009-0004-2645-4593 Victoria V NefedovaResearch Centre of Biotechnology, Russian Academy of Sciences, 119071 Moscow, Russia.
Funding
Russian Science Foundation 24-74-00128
6 · The paper itselfAbstract
Tropomyosins (Tpm) are the family of actin-binding proteins encoded by four genes in humans. Missense mutations in the
Indexed as
CardiomyopathiesCytoplasmMutationTropomyosinActinsAnimalsHumansMutation, MissenseProtein BindingProtein IsoformsActinsProtein IsoformsTPM1 protein, humanTropomyosinactin cytoskeleton dynamicsactin filamentscardiomyopathiescytoplasmic isoforms of tropomyosindifferential scanning calorimetryoptical trap
Identifiers
PMID42280091
PMCPMC13257816
What Socratic holds
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