ReviewSensors (Basel, Switzerland)2026
Advances in Zn-MOF-Based Materials for Electrochemical and Fluorescence Sensing Applications.
Review in Sensors (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Authors and funding
3 authors.
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Abstract
Metal-organic frameworks (MOFs) exhibit high specific surface area and porosity, which may facilitate electron transfer during electrochemical reactions. Therefore, it is clear that MOFs are promising materials for the development of electrochemical sensors. In particular, zinc (Zn) based MOFs offer several advantages such as high specific surface area, porosity, environmental friendliness and low cost. Thus, Zn-based MOF materials and their composites have been extensively utilized in the detection of various pollutants, biomolecules and food additives. The Zn-MOF-based materials have been extensively utilized in electrochemical and fluorescence sensing applications. Previously, various Zn-MOF-based sensing systems such as pristine Zn-MOF, carbon-supported Zn-MOF composites, MXene hybrids with Zn-MOF, and bimetallic/trimetallic Zn-based MOFs were explored to enhance sensing performance. Such materials exhibit remarkable analytical performance, such as a low limit of detection (LOD) (nM to pM range), wide linear response range (LR), fast response times, and high selectivity in the presence of interfering species. In electrochemical sensing, Zn-MOF-modified electrodes demonstrated improved charge-transfer kinetics and sensitivity, enabling accurate determination of the biomolecules, drugs and heavy metal ions in real samples. Similarly, Zn-MOF-based fluorescence sensors showed high luminescent properties and displayed sensitive detection of pollutants and biomolecules. Despite such promising sensing performances, some challenges, such as low stability, reproducibility and selectivity in real-time monitoring, etc., remain that need to be overcome. This review article summarizes the previously reported literature on the fabrication of Zn-MOFs, their composites and Zn-MOF-derived materials for the development of electrochemical and fluorescence sensors. We have also discussed the future directions for the rational design of the high-performance Zn-MOF-based sensing systems for environmental and biomedical applications. We believe that the present review article would be useful for the scientific community working on the fabrication of Zn-MOF-based sensors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.