Evidence map›Paper›PMID 42282158›Full record

ArticlemedRxiv : the preprint server for health sciences2026

Disruption of CTCF binding by germline non-coding variants in

Jessica L Scales, Jayne A Barbour, Alisa M Goldstein, Rebecca Hennessey, Mai Xu, Abigail J Dennis, Sophie Papiernik, Jung Kim, Sudipto Das, Haocheng Yang and 25 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Jessica L ScalesDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Jayne A BarbourSchool of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR, China.
Alisa M GoldsteinDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Rebecca HennesseyDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Mai XuDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Abigail J DennisDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Sophie PapiernikDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Jung KimDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Sudipto DasCCR Protein and Metabolite Characterization Core (PMCC), Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA.
Haocheng YangSchool of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR, China.
S Chul KwonSchool of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR, China.
Kornelia GladyszSchool of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR, China.
Rohit ThakurDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Joshuah YonDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Linh Bui-RabornDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Douglas R StewartDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Raj ChariGenome Modification Core, Laboratory Animal Sciences Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
Paula L HylandDivision of Applied Regulatory Science, Center for Drug Evaluation and Research, US Food and Drug Administration, Chevy Chase, MD, USA.
Jiyeon ChoiDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Tongwu ZhangDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Wen LuoDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Kedest TeferiDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Thorkell AndressonCCR Protein and Metabolite Characterization Core (PMCC), Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA.
Xin LiDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Kristine M JonesDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Amy HutchinsonDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Belynda D HicksDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
W Ryan DiverDepartment of Population Science, American Cancer Society, Atlanta, GA, USA.
Adriana LoriDepartment of Population Science, American Cancer Society, Atlanta, GA, USA.
Steven C MooreDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Margaret A TuckerDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Michael R SargenDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.
Kevin M BrownDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.ORCID 0000-0002-8558-6711
Jason W H WongSchool of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR, China.
Xiaohong R YangDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA.

Funding

WORK ORDER 126643 B539 EXPAND IC SUITE75N91019D00024 · NIAID · LEIDOS BIOMEDICAL RESEARCH, INC. · PI BRISCOE, LYNN · 2019 to 2025
$3932.6M
NIH HHS 75N91019D00024
6 · The paper itself

Abstract

Some melanoma-prone families linked to the 9p21 locus, harboring the established susceptibility gene

Identifiers

PMID42282158
PMCPMC13252464

What Socratic holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.