ArticleBioinformation2026
Short-term effectiveness of three agents for dentin hypersensitivity treatment: A randomized clinical trial.
Article in Bioinformation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dentin hypersensitivity is common and many desensitizing agents exist, but comparative data across products and delivery methods remain limited. Therefore, it is of interest to compare three interventions-GLUMA Desensitizer, Clinpro XT Fluoride Varnish and 1.23% APF gel with iontophoresis applied in 75 patients using two stimuli (cold air blast and explorer scratching) and assessed by VAS at six time points up to 120 days. All three groups showed significant reductions in hypersensitivity over time on both stimuli, with the greatest VAS decline seen in the APF-iontophoresis group, particularly under air blast stimulation (mean change 63.28 ±12.80; p < 0.001). No significant intergroup differences were observed with explorer scratching, suggesting stimulus-dependent discrimination of efficacy. Thus, we show that 1.23% APF gel with iontophoresis provides the most sustained and clinically meaningful relief, supporting its preferential use for long-term management of air-induced dentin hypersensitivity.
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