ArticleClinical oral implants research2026
Collagen Membrane Fixation Technique Affects Its Space Maintenance Capacity After Flap Closure: An Ex Vivo Analysis.
Article in Clinical oral implants research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
aimsTo quantify immediate graft displacement following tension-free flap closure in non-contained alveolar ridge defects regenerated using three membrane fixation strategies in an ex vivo human model.
methodsEighteen sites from six fresh cadaveric heads with non-contained defects underwent horizontal guided bone regeneration using deproteinized bovine bone mineral and a collagen membrane stabilized by no fixation (NF), periosteal sutures (PS), or titanium fixation pins (FP). Techniques were applied sequentially. Cone-beam CT scans were obtained at baseline, post-grafting, and after passive closure. Linear ridge width was measured at 12 standardized positions, and graft volumes were segmented from STL reconstructions. Mixed-effects multilevel linear regression assessed width changes, while Friedman and paired Wilcoxon tests evaluated volumetric outcomes, with Tukey-adjusted contrasts for intergroup comparisons.
resultsFixation pins virtually eliminated graft displacement (-6.7 ± 87 mm
conclusionEven after passive flap release and tension-free closure, membrane fixation, particularly with titanium pins, provides superior resistance to graft displacement in non-contained defects, while unfixed membranes allow substantial graft loss and are therefore not recommended in non-contained defects.
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