Evidence mapPaperPMID 42284361Full record

ArticlePloS one2026

Dynamic analysis of critical maternal complications in tertiary hospitals in Wuxi: A study based on four years of monitoring data.

Ye Xu, Peimin Hua, Ye Shen

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Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Ye XuDepartment of Community Health, Wuxi Maternity and Child Health Care Hospital, Wuxi, Jiangsu Province, China.
Peimin HuaDepartment of Obstetrics, Wuxi Maternity and Child Health Care Hospital, Wuxi, Jiangsu Province, China.
Ye ShenReproductive Health and Family Planning Department Wuxi Maternity and Child Health Care Hospital, Wuxi, Jiangsu Province, China.ORCID https://orcid.org/0000-0002-0511-4125

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere maternal morbidity (SMM) is a significant public health concern. This study analyzed the incidence, trends, causes, and pregnancy outcomes of SMM in Wuxi to inform future clinical and public health strategies.

methodsA retrospective analysis was conducted on 315 critical maternal cases identified from 156,435 deliveries in Wuxi between October 1, 2020, and September 30, 2024. Data were extracted from a citywide near-miss maternal surveillance system. Statistical analyses were performed using SPSS 25.0, employing chi-square tests and Cochran-Armitage trend tests to evaluate trends, and chi-square tests for comparisons between groups.

resultsThe overall incidence of SMM was 0.20%. Initially, this rate remained stable at 0.19% across the first three cycles (P > 0.05); however, it significantly increased to 0.24% during the cycle from October 2023 to September 2024 (χ² = 5.24, P = 0.02). This increase was closely associated with a rise in the proportion of women of advanced maternal age (≥35 years), which reached 26.03% (χ² = 11.76, P = 0.001). Over time, the distribution of risk levels shifted. Initially, the high-risk group was dominant (63.29%), but in recent cycles, the moderate-risk group became more prominent (64.44%). The moderate-risk group was associated with a higher rate of adverse outcomes (25.00-25.71%) compared to the high-risk group (17.11-20.69%; χ² = 10.83, P = 0.01). Direct obstetric factors were the primary causes, accounting for 79.05% of cases, with obstetric hemorrhage being the most prevalent (53.97%). In contrast, the proportion of cases attributable to indirect obstetric factors increased from 17.81% to 26.67%, primarily due to heart disease and infectious diseases.

conclusionImproving maternal safety involves dynamic risk assessments, tiered referrals for moderate-risk pregnancies, better multidisciplinary management of complications, optimized emergency responses in primary care, and refined regional referral systems to reduce preventable SMM and mortality.

Indexed as

Pregnancy ComplicationsTertiary Care CentersAdultAdvanced Maternal AgeChinaFemaleHumansIncidencePregnancyPregnancy OutcomeRetrospective Studies

Identifiers

PMID42284361
PMCPMC13262940

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.