Evidence map›Paper›PMID 42285333›Full record

ArticleArchives of physical medicine and rehabilitation2026

Profiles of Quality of Life Outcomes Observed in Rehabilitation Patients Using Latent Profile Analysis.

Callie E Tyner, Aaron J Boulton, Pamela A Kisala, Nancy D Chiaravalloti, Heather B Taylor, Mark Sherer, Jerry Slotkin, David S Tulsky

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of physical medicine and rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Examining the factor structure of health-related quality of life in spinal cord injury using confirmatory factor analysis and multidimensional scaling.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Callie E TynerCenter for Health Assessment Research and Translation, University of Delaware, Newark, DE. Electronic address: ctyner@udel.edu.
Aaron J BoultonCenter for Health Assessment Research and Translation, University of Delaware, Newark, DE.
Pamela A KisalaCenter for Health Assessment Research and Translation, University of Delaware, Newark, DE.
Nancy D ChiaravallotiCenter for Neuropsychology & Neuroscience Research, Kessler Foundation, NJ; Department of Physical Medicine and Rehabilitation, Rutgers University, Newark, NJ.
Heather B TaylorBrain Injury Research Center, TIRR Memorial Hermann, Houston, TX.
Mark ShererBrain Injury Research Center, TIRR Memorial Hermann, Houston, TX; Casa Colina Research Institute, Poxmona, CA.
Jerry SlotkinCenter for Health Assessment Research and Translation, University of Delaware, Newark, DE.
David S TulskyCenter for Health Assessment Research and Translation, University of Delaware, Newark, DE; Department of Physical Therapy, University of Delaware, Newark, DE; Department of Psychological and Brain Sciences, University of Delaware, Newark, DE.

Funding

Measuring Symptom Clusters in People with Sudden-Onset DisabilitiesR01NR018684 · NINR · UNIVERSITY OF DELAWARE · PI TULSKY, DAVID SCOTT · 2019 to 2024
$3.7M
NINR NIH HHS R01 NR018684
6 · The paper itself

Abstract

objectiveTo explore patterns of quality of life (QOL) outcomes in a diverse group of patients commonly seen in rehabilitation settings, in an effort to understand shared profiles of experiences that cut across diagnostic groupings.

designCross-sectional study.

settingAcademic research center.

participantsEnglish-speaking adults with a medically confirmed history of traumatic brain injury, spinal cord injury, stroke, or major limb injury and/or limb loss because of a sudden-onset cause, recruited from 3 clinical sites in the US.

interventionsNot applicable. MAIN OUTCOME AND MEASURES: Standardized factor scores computed for 9 outcome cluster factor scores based on patient-reported outcome measures of economic QOL, fatigue/sleep, pain, independence, physical function, negative affect, positive affect, and social health, and cognitive measures from the brief test of adult cognition by telephone.

resultsOptimal model fit for the latent profile analysis was achieved with a 4-profile model. These profiles were found to cut across clinical condition and were distinguished by a number of outcomes beyond symptom severity. Pain, independence, cognition, and social participation varied in important ways across the profiles.

conclusionsThis study supported the use of outcome cluster profiles as part of rehabilitation treatment, in addition to information about one's clinical condition when conceptualizing patient needs. The findings reported here may be useful for developing distinct rehabilitation management approaches based on these outcome cluster profiles.

Indexed as

AmputationBrain injuriesOrthopedicsPatient reported outcome measuresPrecision medicineQuality of lifeRehabilitationSpinal cord injuriesStroke

Identifiers

PMID42285333
PMCPMC13337145

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.