Evidence map›Paper›PMID 42286607›Full record

ArticleBMC women's health2026

Dysmenorrhea patients' experience with work productivity impact and treatment in Japan.

Osamu Hiraike, Daisuke Goto, Masahiko Uchiyama, Shoko Takahashi, Yutaka Osuga

Abstract read
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Article in BMC women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Osamu HiraikeDepartment of Obstetrics and Gynecology, Nippon Medical School Hospital, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, Japan.ORCID 0000-0002-3458-6711
Daisuke GotoOrganon, 30 Hudson Street, Jersey City, New Jersey, USA. daisuke.goto1@organon.com.ORCID 0000-0003-4921-3851
Masahiko UchiyamaOrganon, 1-24-3 Minamiaoyama, Minato-ku, Tokyo, Japan.
Shoko TakahashiOrganon, 1-24-3 Minamiaoyama, Minato-ku, Tokyo, Japan. shoko.takahashi@organon.com.ORCID 0000-0003-4050-8100
Yutaka OsugaTeikyo Academic Research Center, Teikyo University, 2-11-1 Kaga, Tokyo, Itabashi-ku, Japan.ORCID 0000-0002-6660-1066

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNearly 50% of Japanese women report impaired work performance due to menstrual symptoms. Our objectives were to describe the real-world experiences of patients living with dysmenorrhea with a focus on work productivity and its association with treatments. Our exploratory objective was to understand the coping methods for menstrual pain in Japanese women.

methodsUsing an anonymized database consisting of linked Japanese health insurance claims and Work Productivity and Activity Impairment Questionnaire - General Health (WPAI-GH) responses for women aged between 18 and 50 years, we conducted descriptive analyses of work productivity impact among patients with dysmenorrhea, other chronic diseases and individuals without medical records. Analysis of work productivity impact was conducted per dysmenorrhea treatment. The analyses were descriptive and unadjusted thus the generalizability and external validity of differences between conditions and treatments are limited.

resultsAmong 9,235 individuals in the employer-sponsored insurance claims database, 956 (10.4%) had diagnosed dysmenorrhea. The unadjusted mean WPAI-GH scores for the dysmenorrhea patient population demonstrated absenteeism at 2.5 ± 0.3% (mean ± standard error) and presenteeism at 26.8 ± 0.9%, similar to groups with mental disorders, headaches, or low back pain. Dysmenorrhea patients receiving low-dose estrogen progestin, also known as combined oral contraceptives, was the largest treatment group and had the lowest mean absenteeism and presenteeism scores among treatment groups in this unadjusted descriptive analysis. In 5,471 respondents who responded on coping methods for menstrual pain, 2,250 (41.1%) used over-the-counter medications, while 329 (6.0%) sought medical care.

conclusionThe productivity impact observed in patients with dysmenorrhea was substantial and found to be similar to that of patient groups with major chronic conditions such as mental disorders, headaches, and low back pain. We further found that dysmenorrhea patients' productivity outcomes varied across treatment groups. Whilst prospective studies with adjustment for confounding factors are needed to establish the generalizability of differences between treatment- and condition-based subgroups, our findings underscore the need for greater awareness of dysmenorrhea as a condition that deserves medical attention, and timely medical care may help reduce the burden and improve the quality of life.

Indexed as

AbsenteeismDysmenorrheaEfficiencyPresenteeismWork PerformanceAdaptation, PsychologicalAdolescentAdultFemaleHumansJapanMiddle AgedSurveys and QuestionnairesYoung AdultAbsenteeismActivity impairmentCombined oral contraceptivesDysmenorrheaLow-dose estrogen–progestinMenstrual painPresenteeismTreatment patternWork Productivity and Activity Impairment Questionnaire - General Health (WPAI)Work productivity loss

Identifiers

PMID42286607
PMCPMC13488208

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.