ArticleJournal of nanobiotechnology2026
Acceleration of DNA reactions on the algae-based microrobots.
Article in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
DNA reactions on solid surfaces often suffer from low efficiency due to limited mass transfer and slow reaction kinetics, which greatly limits their biomedical applications. Here, we report a strategy to construct dynamic DNA biointerfaces based on moveable algal microrobots (AMs), whose autonomous motion-generated micro-hydrodynamics profoundly affects interfacial DNA reactions. After immobilizing DNA strands on the AMs, we uncover that the swimming speed of these microrobots is positively correlated with the kinetics of different DNA reactions from simple hybridization to complex enzymatic/nonenzymatic amplification reactions. This "motion-enhanced" effect mainly stems from the convection and mixing generated around the swimming cells, which greatly improve mass transfer velocity, thereby reducing hybridization times to minutes and enhance reaction efficiency. As a result, this feature is demonstrated to be useful in achieving ultrafast molecular recognition, ultrasensitive nucleic acid detection, and autonomous cell assembly in complex biological media. Our work provides a paradigm shift for overcoming the reaction efficiency bottleneck of DNA interface and paves a new avenue for designing intelligent bio-hybrid systems.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.