Evidence map›Paper›PMID 42289596›Full record

ArticleHeart and vessels2026

Coronary intimal proliferation despite lipid reduction during the first year after heart transplantation.

Tatsuya Shiraki, Tomohito Ohtani, Isamu Mizote, Daisuke Nakamura, Yasumasa Tsukamoto, Kosuke Takahari, Yasuhiro Akazawa, Kei Nakamoto, Shumpei Kosugi, Shota Okuno and 5 more

Abstract read
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In one paragraph

Article in Heart and vessels, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tatsuya ShirakiDepartment of Cardiovascular Medicine, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Tomohito OhtaniDepartment of Cardiovascular Medicine, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. ohtani@cardiology.med.osaka-u.ac.jp.ORCID http://orcid.org/0000-0002-2963-7895
Isamu MizoteDepartment of Cardiovascular Medicine, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Daisuke NakamuraDepartment of Cardiovascular Medicine, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Yasumasa TsukamotoDepartment of Transplant Medicine, National Cerebral and Cardiovascular Center, Suita, Japan.
Kosuke TakahariDepartment of Cardiovascular Medicine, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Yasuhiro AkazawaDepartment of Cardiovascular Medicine, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Kei NakamotoDepartment of Cardiology, Osaka Police Hospital, Osaka, Japan.
Shumpei KosugiDepartment of Cardiovascular Medicine, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Shota OkunoDepartment of Cardiovascular Medicine, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Hidetaka KiokaDepartment of Cardiovascular Medicine, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Yasuharu TakedaDepartment of Cardiovascular Medicine, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Yuto OhtaDepartment of Clinical Engineering, Osaka University Hospital, Suita, Japan.
Shigeru MiyagawaDepartment of Cardiovascular Surgery, The University of Osaka Graduate School of Medicine, Suita, Japan.
Yasushi SakataDepartment of Cardiovascular Medicine, The University of Osaka Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.

Funding

JSPS KAKENHI 17K16005The Osaka Heart Club The Osaka Heart Club
6 · The paper itself

Abstract

Cardiac allograft vasculopathy (CAV) is a major cause of mortality after heart transplantation, characterized by intimal proliferation-induced coronary stenosis. The first year post-transplantation represents a critical period for CAV development, with most intimal proliferation occurring during this timeframe. This study aimed to investigate the temporal changes in lipid content and its relationship with intimal proliferation during the first year after heart transplantation. Serial three-vessel near-infrared spectroscopy intravascular ultrasound (NIRS-IVUS) and optical coherence tomography (OCT) were performed in 15 heart transplant recipients (38 coronary arteries) at 2 months (baseline) and 12 months (follow-up) following heart transplantation. From baseline to follow-up, the highest lipid-core burden index within a 4 mm segment (maxLCBI

Indexed as

Cardiac allograft vasculopathyHeart transplantationIntravascular ultrasoundLipid-core burden indexNear-infrared spectroscopy

Identifiers

PMID42289596

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.