ArticleClinical case reports2026
Cutaneous Mucormycosis Clinically Mimicking Necrotizing Fasciitis in a Patient Without Active Immunosuppression.
Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cutaneous mucormycosis is a rare invasive fungal infection caused by fungi of the order Mucorales. Although it classically occurs in immunocompromised hosts, traumatic or minor cutaneous inoculation may result in infection even in patients without active immunosuppression. Because vascular invasion may lead to rapidly progressive necrosis, cutaneous mucormycosis can clinically resemble necrotizing soft-tissue infection. A 70-year-old man with a history of laryngeal carcinoma in remission and no active immunosuppressive treatment presented with 1 week of progressive pain, swelling, discoloration, and necrotic lesions of the left leg. Necrotizing fasciitis was clinically suspected because of severe pain, extensive hemorrhagic necrosis along the fascia, and deep soft-tissue involvement; however, no computed tomography or magnetic resonance imaging was performed. Tissue sampling showed broad, pauciseptate hyphae with right-angle branching on direct microscopy, and fungal culture grew Mucorales species. Liposomal amphotericin B was initiated at 5 mg/kg/day, but treatment was discontinued after serum creatinine increased from 0.81 to 2.5 mg/dL despite hydration. Intravenous posaconazole was started, followed by oral posaconazole delayed-release tablets after discharge. Therapeutic drug monitoring was not available. Serial debridements, antifungal therapy, and subsequent skin grafting resulted in clinical recovery without relapse during follow-up. This case highlights that cutaneous mucormycosis may present with necrotizing deep soft-tissue involvement and clinically mimic necrotizing fasciitis. The case also underlines the need to avoid overstatement of host immune status when advanced age and previous malignancy are present. Early surgical management, tissue-based mycological diagnosis, and prompt antifungal therapy remain essential; posaconazole is a useful step-down or salvage option when amphotericin B toxicity limits treatment, but formulation and therapeutic drug monitoring should be considered.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.